54 studies found for:    Tuberous Sclerosis
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Rank Status Study
1 Recruiting Early Biomarkers of Autism in Infants With Tuberous Sclerosis Complex (TSC)
Condition: Tuberous Sclerosis Complex
Intervention:
2 Recruiting Genetic Heterogeneity and Genotype-phenotype Correlation of Children and Adults With Tuberous Sclerosis Complex
Conditions: Sclerosis Tuberosa;   Tuberous Sclerosis Complex;   Cerebral Sclerosis;   Nervous System Disorders
Intervention:
3 Recruiting Autism Spectrum Disorder (ASD) and Intellectual Disability (ID) Determinants in Tuberous Sclerosis Complex (TSC)
Conditions: Tuberous Sclerosis;   Autism Disorder;   Intellectual Disability
Intervention:
4 Completed
Has Results
Efficacy and Safety of Everolimus (RAD001) in Patients of All Ages With Subependymal Giant Cell Astrocytoma Associated With Tuberous Sclerosis Complex (TSC)(EXIST-1)
Conditions: Tuberous Sclerosis;   Subependymal Giant Cell Astrocytoma
Interventions: Drug: Everolimus;   Drug: Placebo
5 Completed Rapamycin Therapy for Patients With Tuberous Sclerosis Complex and Sporadic LAM
Conditions: Tuberous Sclerosis;   Lymphangioleiomyomatosis
Intervention: Drug: Rapamycin, sirolimus
6 Completed
Has Results
Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis Complex (TSC) or Sporadic Lymphangioleiomyomatosis (LAM)
Conditions: Tuberous Sclerosis Complex (TSC);   Lymphangioleiomyomatosis (LAM)
Interventions: Drug: Everolimus (RAD001);   Drug: Placebo
7 Recruiting Study of Skin Tumors in Tuberous Sclerosis
Conditions: Hereditary Neoplastic Syndrome;   Tuberous Sclerosis
Intervention:
8 Unknown  Tuberous Sclerosis Complex Natural History Study: Renal Manifestations
Condition: Tuberous Sclerosis Complex
Intervention:
9 Completed Trial of RAD001 and Neurocognition in Tuberous Sclerosis Complex (TSC)
Condition: Tuberous Sclerosis Complex
Intervention: Drug: RAD001
10 Completed
Has Results
Everolimus (RAD001) Therapy of Giant Cell Astrocytoma in Patients With Tuberous Sclerosis Complex
Conditions: Tuberous Sclerosis;   Subependymal Giant Cell Astrocytoma
Intervention: Drug: Everolimus
11 Recruiting A Study of Everolimus in the Treatment of Neurocognitive Problems in Tuberous Sclerosis
Condition: Tuberous Sclerosis
Interventions: Drug: Placebo;   Drug: Everolimus (RAD001)
12 Completed Everolimus (RAD001) Therapy for Epilepsy in Patients With Tuberous Sclerosis Complex (TSC)
Conditions: Epilepsy;   Tuberous Sclerosis Complex
Intervention: Drug: Everolimus
13 Not yet recruiting Long-term Trial of Topical Sirolimus to Angiofibroma in Patient With Tuberous Sclerosis Complex
Conditions: Tuberous Sclerosis;   Angiofibroma;   Hypomelanotic Macule;   Plaque
Intervention: Drug: NPC-12G gel
14 Recruiting Efficacy of RAD001/Everolimus in Autism and NeuroPsychological Deficits in Children With Tuberous Sclerosis Complex
Conditions: Tuberous Sclerosis Complex;   TSC Related Cognitive Disability;   TSC Related Autism;   TSC Related Learning Problems
Interventions: Drug: Everolimus;   Drug: Placebo
15 Completed Topical Rapamycin Therapy to Alleviate Cutaneous Manifestations of Tuberous Sclerosis Complex (TSC) and Neurofibromatosis I (NF1)
Conditions: Tuberous Sclerosis;   Neurofibromatoses;   Angiofibroma;   Neurofibroma
Interventions: Drug: Skincerity;   Drug: Skincerity plus sirolimus/rapamycin;   Drug: Skinercity plus sirolimus/rapamycin
16 Not yet recruiting Phase III Trial of Topical Formulation of Sirolimus to Skin Lesions in Patients With Tuberous Sclerosis Complex (TSC)
Conditions: Tuberous Sclerosis;   Angiofibroma;   Hypomelanotic Macule;   Plaque
Interventions: Drug: NPC-12G gel;   Drug: Placebo gel
17 Recruiting Treatment of Renal Angiomyolipomas in Tuberous Sclerosis by Beta-blockers
Conditions: Renal Angiomyolipomas;   Tuberous Sclerosis
Intervention: Drug: Propranolol
18 Completed Long Term Follow Up for RAD001 Therapy of Angiomyolipomata in Patients With Tuberous Sclerosis (TSC) and Sporadic Lymphangioleiomyomatosis (LAM)
Conditions: Tuberous Sclerosis;   Angiolipoma
Intervention: Drug: everolimus (RAD001)
19 Not yet recruiting Characterization of Patients With Tuberous Sclerosis Complex, Lymphangioleiomyomatosis and Angiomyolipoma
Conditions: Tuberous Sclerosis;   Lymphangioleiomyomatosis;   Angiomyolipoma
Intervention:
20 Unknown  Trial of Efficacy and Safety of Sirolimus in Tuberous Sclerosis and LAM
Conditions: Tuberous Sclerosis;   Lymphangioleiomyomatosis
Intervention: Drug: sirolimus

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Indicates status has not been verified in more than two years