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203 studies found for:    Ataxia

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Rank Status Study
1 Recruiting Sporadic Degenerative Ataxia With Adult Onset: Natural History Study
Condition: Late Onset Sporadic Cerebellar Ataxia
Intervention:
2 Recruiting Natural History Study of and Genetic Modifiers in Spinocerebellar Ataxias
Conditions: Spinocerebellar Ataxia Type 1;   Spinocerebellar Ataxia Type 2;   Spinocerebellar Ataxia Type 3;   Spinocerebellar Ataxia Type 6
Intervention: Genetic: All Participants
3 Completed Preliminary Study of the Scale To Assess Ataxia and Neurologic Dysfunction (STAND)
Conditions: Spinocerebellar Ataxia - All Sub-types;   Friedreich's Ataxia
Intervention: Other: Ataxia rating scale
4 Completed Biomarkers in Autosomal Dominant Cerebellar Ataxia
Conditions: Spinocerebellar Ataxia Type 1;   Spinocerebellar Ataxia Type 2;   Spinocerebellar Ataxia, Autosomal Recessive 3;   Episodic Ataxia, Type 7
Intervention: Other: metabolic and imaging biomarkers in SCA1,2,3 and 7 patients
5 Enrolling by invitation 4-Aminopyridine in Episodic Ataxia Type 2
Condition: Episodic Ataxia Type 2
Interventions: Drug: 4-Aminopyridine;   Drug: Placebo
6 Recruiting Biomarkers in Friedreich's Ataxia
Condition: Friedreich's Ataxia
Intervention:
7 Recruiting Functional and Structural Imaging and Motor Control in Spinocerebellar Ataxia
Condition: Spinocerebellar Ataxia
Interventions: Behavioral: Error-reduction;   Behavioral: International Cooperative Ataxia Rating Scale;   Behavioral: Scale for the Assessment and Rating of Ataxia;   Behavioral: Beck Depression Inventory, 2nd Ed;   Behavioral: Stroop;   Behavioral: Purdue Pegboard;   Behavioral: Brief Test of Attention;   Behavioral: 6-minute Walk;   Behavioral: Hand Grip Dynamometer;   Behavioral: Montreal Cognitive Assessment;   Behavioral: Physical Performance Function;   Behavioral: Biomechanical Assessments of Dysmetria;   Behavioral: Neurophysiological assessment of brain activity;   Behavioral: Biomechanical gait analysis
8 Completed Effect of Riluzole as a Symptomatic Approach in Patients With Chronic Cerebellar Ataxia
Conditions: Hereditary Ataxia;   Multiple Sclerosis;   Cerebellar Ataxia
Interventions: Drug: Riluzole;   Other: placebo
9 Completed Safety Study of Carbamylated Erythropoietin to Treat Patients With the Neurodegenerative Disorder Friedreich's Ataxia
Condition: Friedreich's Ataxia
Interventions: Drug: Lu AA24493;   Drug: Placebo
10 Completed
Has Results 		Interferon Gamma-1b in Friedreich Ataxia (FRDA)
Condition: Friedreich Ataxia
Intervention: Drug: Interferon Gamma-1b
11 Completed Efficacy of Riluzole in Hereditary Cerebellar Ataxia
Condition: Cerebellar Ataxia
Interventions: Drug: riluzole;   Drug: Placebo comparator
12 Completed A Study of Resveratrol as Treatment for Friedreich Ataxia
Condition: Friedreich Ataxia
Intervention: Drug: Resveratrol
13 Enrolling by invitation Early and Longitudinal Assessment of Neurodegeneration in the Brain and Spinal Cord in Friedreich's Ataxia
Condition: Friedreich Ataxia
Intervention:
14 Active, not recruiting Transcranial Magnetic Stimulation in Spino-Cerebellar Ataxia
Condition: Spinocerebellar Ataxia
Intervention: Device: Transcranial Magnetic Stimulation
15 Recruiting Augmenting Balance in Individuals With Cerebellar Ataxias
Condition: Cerebellar Ataxia
Intervention: Behavioral: Sensory Augmentation
16 Recruiting Methylprednisolone Treatment of Friedreich Ataxia
Condition: Friedreich Ataxia
Intervention: Drug: Methylprednisolone
17 Enrolling by invitation Susceptibility to Infections in Ataxia Telangiectasia
Conditions: Ataxia Telangiectasia;   Infections;   Immunodeficiency;   Lung Disease
Interventions: Procedure: Blood collection;   Procedure: Lung function measurement;   Behavioral: Symptom diary
18 Recruiting Clinical Study to Evaluate the Safety and Efficacy BMMNC in Cerebellar Ataxia
Condition: Cerebellar Ataxia
Intervention: Biological: Intravenous transfer of of Bone Marrow derived Mono Nuclear Stem Cell (BMMNCs)
19 Completed
Has Results 		Study to Assess the Safety and Tolerability of Idebenone in the Treatment of Friedreich's Ataxia Patients
Condition: Friedreich's Ataxia
Intervention: Drug: Idebenone
20 Recruiting RTA 408 Capsules in Patients With Friedreich's Ataxia - MOXIe
Condition: Friedreich Ataxia
Interventions: Drug: Omaveloxolone Capsules, 2.5 mg;   Drug: Omaveloxolone Capsules, 5 mg;   Drug: Omaveloxolone Capsules, 10 mg;   Drug: Placebo;   Drug: Omaveloxolone Capsules, 20 mg;   Drug: Omaveloxolone Capsules, TBD mg;   Drug: Omaveloxolone Capsules, 40 mg;   Drug: Omaveloxolone Capsules, 80 mg;   Drug: Omaveloxolone Capsules, 160 mg
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† Indicates status has not been verified in more than two years