To determine if 6 weeks of treatment with sertraline (50 mg daily for 2 weeks, followed by 100 mg per day for 4 weeks, if tolerated) results in greater reduction in hot flush score (frequency x severity), frequency and severity compared to placebo
To determine the effect of treatment with sertraline on quality of life, sleep, sexual function, and mood. To determine if a modified, short version of a sexual function instrument is valid.
40 Years to 60 Years (Adult)
January 27, 2006
August 4, 2006
UCSF Women's Health Clinical Research Center San Francisco, California, United States
† Study has passed its completion date and status has not been verified in more than two years.