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57 studies found for:    Open Studies | "Thalassemia"
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Rank Status Study
1 Recruiting Gene Therapy for Transfusion Dependent Beta-thalassemia
Condition: Beta-Thalassemia
Intervention: Genetic: Autologous hematopoietic stem cells genetically modified with GLOBE lentiviral vector encoding for the human beta-globin gene
2 Recruiting Reproductive Capacity and Iron Burden in Thalassemia
Condition: THALASSEMIA MAJOR
Interventions: Other: Blood Draw/Semen Exam;   Other: Retrospective data/Chart Review/Relevant Clinical Results;   Other: Pituitary MRI
3 Recruiting Efficacy of Basiliximab in the Prevention of Acute Graft-versus-host Disease in Unrelated Allogeneic Hematopoietic Stem Cell Transplantation Therapy for Thalassemia Major
Condition: Beta-Thalassemia Major
Interventions: Drug: Basiliximab,;   Drug: cyclosporine A;   Drug: Methotrexate;   Drug: Mycophenolate mofetil
4 Recruiting Monitoring of Chimerism After Transplantation in Patients With β Thalassemia Major and the Treatment Strategies for the Reduction of Chimerism
Condition: Beta Thalassemia Major
Interventions: Drug: Interleukin-2;   Drug: Donor Regulatory T-Lymphocytes
5 Not yet recruiting A Study of EPEG in Beta Thalassemia Patients
Condition: Beta-Thalassemia
Intervention: Drug: EPEG (Pegylated erythropoeitin)
6 Recruiting Allograft for Sickle Cell Disease and Thalassemia
Condition: Sickle Cell Disease and Thalassemia
Intervention: Biological: Donor Stem Cell Transplantation
7 Recruiting A Study Evaluating the Efficacy and Safety of the LentiGlobin® BB305 Drug Product in Subjects With Transfusion-Dependent β-Thalassemia
Condition: Beta-Thalassemia
Intervention: Genetic: LentiGlobin BB305 Drug Product
8 Recruiting Haploidentical Hematopoietic Stem Cell Transplantation for Children With Sickle Cell Disease and Thalassemia Using CD34+ Positive Selected Grafts
Conditions: Sickle Cell-thalassemia Disease;   Thalassemia
Intervention: Drug: peripheral blood stem cell graft that are CD34+ selected
9 Recruiting Benefits of Nigella Sativa in Children With Beta Thalassemia Major
Condition: Nigella Sativa With Beta Thalassemia Major
Intervention: Drug: nigella sativ
10 Recruiting Screening for Alpha Thalassemia in Healthy Volunteers
Condition: Alpha Thalassemia
Intervention:
11 Recruiting Detection of β Thalassemia Carriers by Red Cell Parameters Obtained From the H2 Automatic Counter
Conditions: Thalassemia;   Iron Deficiency
Intervention: Procedure: Observation of results from laboratory tests
12 Recruiting An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Adults Who Require Regular Red Blood Cell Transfusions Due to Beta (β) Thalassemia
Conditions: Erythrocyte Transfusion;   Beta-Thalassemia
Interventions: Drug: Luspatercept;   Other: Placebo
13 Recruiting Therapeutic Effect of Colla Corii Asini on Improving Anemia and Hemoglobin Composition in Pregnant Women With Thalassemia
Condition: Thalassemia
Intervention: Drug: Colla corii asini
14 Recruiting Stem Cell Transplant in Sickle Cell Disease and Thalassemia
Conditions: Sickle Cell Disease;   Beta Thalassemia
Interventions: Drug: Busulfan;   Drug: Fludarabine;   Drug: Alemtuzumab;   Procedure: Allogeneic stem cell transplant
15 Not yet recruiting Denosumab Versus Zoledronic Acid in Thalassemia-Induced Osteoporosis
Conditions: Thalassemia Majors (Beta-Thalassemia Major);   Osteoporosis
Interventions: Drug: Denosumab 60 MG/ML Prefilled Syringe;   Drug: Zoledronic Acid 5Mg/Bag 100Ml Inj
16 Not yet recruiting Sofosbuvir/Ledipasvir for Hepatitis C Genotype 1-6 in Patients With Transfusion-Dependent Thalassemia: An Open Label Trial
Conditions: Thalassemia;   Hepatitis C
Intervention: Drug: sofosbuvir/velpatasvir
17 Recruiting Amlodipine as Adjuvant Treatment to Iron Chelation for Prevention of Cardiac Iron Overload in Thalassemia Patients
Conditions: Beta-Thalassemia;   Iron Overload
Interventions: Drug: Amlodipine;   Drug: Deferasirox
18 Not yet recruiting The Potential Hepatoprotective Effect of Metformin in Patients With Beta Thalassemia Major
Condition: Beta Thalassemia Major Anemia
Intervention: Drug: Metformin
19 Recruiting Dose-Escalation Study of SCD-101 in Sickle Cell Disease
Conditions: Sickle Cell Disease;   Sickle-Beta Zero Thalassemia
Intervention: Drug: SCD-101
20 Not yet recruiting Open-label, Multicenter Study Assessing Preference for Deferasirox Film-coated Tablet Compared to Dispersible Tablet
Condition: Transfusion-dependent Thalassemia (TDT) and Non-transfusion-dependent Thalassemia (NTDT)
Interventions: Drug: deferasirox dispersable tablet (DT);   Drug: deferasirox film coated tablet (FCT)

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Study has passed its completion date and status has not been verified in more than two years.