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47 studies found for:    Open Studies | "Oropharyngeal Neoplasms"

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Rank Status Study
1 Recruiting A Study of Mucosal Sparing Proton Beam Therapy (PBT) in Resected Oropharyngeal Tumors
Condition: Oropharyngeal Tumor
Intervention:
2 Unknown † Cetuximab & Concomitant-Boost Accelerated RT in Patients With Locally Advanced Oropharynx Squamous Cell Carcinoma.
Condition: Oropharyngeal Neoplasms
Intervention: Drug: Cetuximab
3 Recruiting Dose Escalation Versus Standard in Laryngopharyngeal Cancers
Conditions: Malignant Neoplasm of Oropharynx Stage III;   Malignant Neoplasm of Larynx Stage III;   Malignant Neoplasm of Hypopharynx Stage III;   Malignant Neoplasm of Oropharynx Stage IVa;   Malignant Neoplasm of Oropharynx Stage IVb;   Malignant Neoplasm of Larynx Stage IV;   Malignant Neoplasm of Hypopharynx Stage IVa;   Malignant Neoplasm of Hypopharynx Stage IVb
Interventions: Radiation: Escalated Dose;   Radiation: Standard Dose
4 Not yet recruiting ACTOplus Met XR in Treating Patients With Stage I-IV Oral Cavity or Oropharynx Cancer Undergoing Definitive Treatment
Conditions: Oral Cavity Neoplasm;   Oropharyngeal Neoplasm;   Stage I Oral Cavity Squamous Cell Carcinoma;   Stage I Oropharyngeal Squamous Cell Carcinoma;   Stage II Oral Cavity Squamous Cell Carcinoma;   Stage II Oropharyngeal Squamous Cell Carcinoma;   Stage III Oral Cavity Squamous Cell Carcinoma;   Stage III Oropharyngeal Squamous Cell Carcinoma;   Stage IVA Oral Cavity Squamous Cell Carcinoma;   Stage IVA Oropharyngeal Squamous Cell Carcinoma;   Stage IVB Oral Cavity Squamous Cell Carcinoma;   Stage IVB Oropharyngeal Squamous Cell Carcinoma;   Stage IVC Oral Cavity Squamous Cell Carcinoma;   Stage IVC Oropharyngeal Squamous Cell Carcinoma
Interventions: Other: Laboratory Biomarker Analysis;   Drug: Metformin Hydrochloride;   Other: Pharmacological Study;   Drug: Pioglitazone Hydrochloride;   Other: Placebo
5 Recruiting A Pilot Study Assessing Robotic Surgery in the Seated Position for Benign and Malignant Lesions of the Head and Neck
Conditions: Oropharyngeal Neoplasms;   Head and Neck Cancer
Intervention: Device: Transoral Robotic Surgery (TORS) with the daVinci Robotic Surgical System device
6 Not yet recruiting Cetuximab, Cisplatin and BYL719 for HPV-Associated Oropharyngeal Squamous Cell Carcinoma
Conditions: Carcinoma, Squamous;   Squamous Cell Carcinoma;   Oropharyngeal Neoplasms;   Oropharyngeal Cancer
Interventions: Drug: cisplatin;   Drug: Cetuximab;   Drug: BYL719
7 Recruiting De-intensification of Radiation and Chemotherapy for Low-Risk HPV-related Oropharyngeal SCC: Follow-up Study
Conditions: Carcinoma, Squamous Cell;   Head and Neck Neoplasms;   Oropharyngeal Neoplasms
Interventions: Radiation: Intensity Modulated Radiotherapy (IMRT);   Drug: Cisplatin (or alternative);   Procedure: Assessment for surgical evaluation
8 Unknown † Analgesia of Fibula Free Flap Donor Site by Peri-Neuronal Catheter in Oro-Pharyngeal Carcinoma Surgery
Condition: Oropharyngeal Neoplasms
Intervention: Device: Peri-Neuronal Catheter
9 Recruiting Evaluation of De-escalated Adjuvant Radiation Therapy for Human Papillomavirus (HPV)-Associated Oropharynx Cancer
Condition: Oropharynx Cancer
Interventions: Radiation: Adjuvant Radiation Therapy;   Drug: Docetaxel;   Drug: Cisplatin
10 Recruiting E7 TCR T Cells With or Without PD-1 Blockade for Human Papillomavirus-Associated Cancers
Conditions: Cervical Cancer;   Vaginal Cancer;   Anal Cancer;   Penile Cancer;   Oropharyngeal Cancer
Interventions: Biological: E7 TCR cells;   Drug: pembrolizumab;   Drug: aldesleukin;   Drug: fludarabine;   Drug: cyclophosphamide
11 Recruiting Image-Guided Stereotactic Radiosurgery (SRS) Boost for HPV-Oropharyngeal Cancer
Condition: Cancer of the Oropharynx
Intervention: Radiation: Stereotactic Radiosurgery
12 Recruiting Cardiopulmonary Fitness in Long-Term Survivors of HPV-related Oropharynx Cancers
Condition: Oropharynx Cancers
Interventions: Other: blood draw;   Behavioral: study questionnaire;   Other: cardiopulmonary exercise testing (CPET);   Other: DXA (dual-energy x-ray absorptiometry) scan
13 Recruiting Pembrolizumab in Combination With CRT for LA-SCCHN
Conditions: Head and Neck Cancer;   Squamous Cell Carcinoma;   Oral Cavity Cancer;   Oropharynx Cancer;   Hypopharynx Cancer;   Larynx Cancer;   Laryngeal Cancer
Interventions: Drug: pembrolizumab (MK-3475);   Drug: Cisplatin;   Radiation: Radiation
14 Recruiting Swallowing, Speech and Quality of Life of Patients With Carcinoma of the Oropharynx
Condition: Squamous Cell Carcinoma of the Oropharynx
Intervention: Procedure: Ability to swallow, speak and quality of life
15 Recruiting Establishing Lymphedema and Fibrosis Measures in Oral Cancer Patients
Conditions: Oral Cavity Cancer;   Oropharyngeal Cancer;   Lymphedema;   Fibrosis
Interventions: Other: LEF measures;   Procedure: Technical measure
16 Recruiting Improving Trans-oral Surgical Outcomes Through Intra-operative Image Guidance
Condition: Oropharyngeal Cancer
Intervention: Other: Intraoperative CT imaging
17 Recruiting HPV-16/18 E6/E7-Specific T Lymphocytes, Relapsed HPV-Associated Cancers, HESTIA
Conditions: Human Papillomavirus-Related Carcinoma;   Human Papillomavirus Positive Oropharyngeal Carcinoma;   Human Papillomavirus Positive Cervical Carcinoma;   Human Papillomavirus Positive Anal Carcinoma;   Human Papillomavirus Positive Vulvar Carcinoma;   Human Papillomavirus Positive Penile Carcinoma
Intervention: Genetic: HPV Specific T Cells
18 Recruiting NBI to Characterize Patterns of Vascular Supply Within Lymphoepithelial Mucosa in Oropharyngeal Cancer
Conditions: Oropharyngeal Carcinoma;   Oropharynx Cancer
Intervention:
19 Recruiting A Pilot Study at a Single-Institution of Pregabalin in the Management of Mucositis Pain in Patients Undergoing Chemoradiation Therapy to the Head and Neck.
Conditions: Oropharyngeal Cancer;   Squamous Cell Carcinoma to the Head and Neck
Intervention: Drug: Lyrica 300 mg
20 Recruiting Nab-paclitaxel and Carboplatin Followed by Response-Based Local Therapy in Treating Patients With Stage III or IV HPV-Related Oropharyngeal Cancer
Conditions: Human Papilloma Virus Infection;   Stage III Squamous Cell Carcinoma of the Oropharynx;   Stage IVA Squamous Cell Carcinoma of the Oropharynx;   Stage IVB Squamous Cell Carcinoma of the Oropharynx
Interventions: Drug: paclitaxel albumin-stabilized nanoparticle formulation;   Drug: carboplatin;   Radiation: radiation therapy;   Drug: paclitaxel;   Drug: fluorouracil;   Drug: hydroxyurea;   Drug: cisplatin;   Other: laboratory biomarker analysis;   Procedure: quality-of-life assessment
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† Indicates status has not been verified in more than two years