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29 studies found for:    Open Studies | "Neurofibromatosis 1"
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Rank Status Study
1 Recruiting Neurofibromatosis Type 1 Patient Registry
Condition: Neurofibromatosis Type 1
Intervention:
2 Recruiting Development and Validation of Patient Reported Outcome (PRO) Measures for Individuals With Neurofibromatosis 1 (NF1) and Plexiform Neurofibromas (PNs)
Conditions: Neurofibromatosis 1;   Plexiform Neurofibromas
Intervention:
3 Recruiting Effect of Lamotrigine on Cognition in NF1
Condition: Neurofibromatosis Type 1
Interventions: Drug: Lamotrigine;   Drug: Placebo
4 Recruiting Hypotonia and Neurofibromatosis Type 1 (NF1) Glioma
Condition: Neurofibromatosis Type 1
Interventions: Device: Magnetic resonance imaging;   Drug: Gadolinium contrast
5 Not yet recruiting Subtle Myocardial Deformation Abnormalities in Asymptomatic Nf-1 Patients
Condition: Neurofibromatosis Type 1
Intervention:
6 Recruiting Efficacy of Computerized Cognitive Training and Stimulant Medication in Neurofibromatosis Type 1
Condition: Neurofibromatosis Type 1
Interventions: Other: CogmedRM;   Other: Mobymax
7 Not yet recruiting Vitamin D Supplementation for Adults With Neurofibromatosis Type 1 (NF1)
Condition: Neurofibromatosis Type 1 (NF1)
Intervention: Drug: Cholecalciferol
8 Recruiting A Study of INFUSE Bone Graft (BMP-2) in the Treatment of Tibial Pseudarthrosis in Neurofibromatosis Type 1 (NF1)
Conditions: NF1;   Congenital Pseudarthrosis of Tibia
Interventions: Device: INFUSE Bone Graft (BMP-2);   Procedure: Control Group
9 Recruiting Photodynamic Therapy for Benign Dermal Neurofibromas
Condition: NEUROFIBROMATOSIS 1
Intervention: Procedure: PDT Treatment
10 Not yet recruiting NF1 Health Sciences Protocol
Conditions: Neurofibromatosis Type 1;   Learning Disability
Interventions: Drug: Lovastatin;   Behavioral: reading tutoring intervention;   Drug: Placebo Oral Tablet;   Behavioral: sham tutoring
11 Recruiting The Cognitive Variability in NF1 and TSC Monozygotic Twins
Conditions: Neurofibromatosis Type I;   Tuberous Sclerosis Complex
Intervention:
12 Recruiting Relationship Stressors in Parents of Children With Cancer or Neurofibromatosis Type 1 (NF1)
Conditions: Parents of Children With Cancer;   Parents of Children With NF1;   Parents of Children With Neurofibromatosis Type I
Intervention:
13 Recruiting Selumetinib in Treating Patients With Neurofibromatosis Type 1 and Plexiform Neurofibromas That Cannot Be Removed by Surgery
Conditions: Neurofibromatosis Type 1;   Plexiform Neurofibroma
Interventions: Other: Laboratory Biomarker Analysis;   Other: Pharmacological Study;   Other: Quality-of-Life Assessment;   Drug: Selumetinib
14 Recruiting Acceptance and Commitment Training for Adolescents and Young Adults With Neurofibromatosis Type 1, Plexiform Neurofibromas, and Chronic Pain
Conditions: Neurofibromatosis Type 1;   Plexiform Neurofibromas
Intervention: Other: Acceptance and Commitment Therapy (ACT)
15 Recruiting Targeting the Mechanisms Underlying Cutaneous Neurofibroma Formation in NF1: A Clinical Translational Approach.
Conditions: Cutaneous Neurofibromas;   Neurofibromatosis Type 1;   Plexiform Neurofibromas
Intervention: Procedure: Skin Biopsy
16 Recruiting A Phase II Trial of the Mitogen Activated Protein Kinase Kinase (MEK1/2) Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in Patients With Neurofibromatosis Type 1 (NF1) Mutated Gastrointestinal Stromal Tumors (GIST)
Conditions: Neoplasms, Nerve Tissue;   Neurofibromatosis 1;   Heredodegenerative Disorders, Nervous System;   Peripheral Nervous System Diseases
Intervention: Drug: Selumetinib (AZD6244 hyd sulfate)
17 Recruiting AZD6244 Hydrogen Sulfate for Children With Nervous System Tumors
Conditions: Neurofibromatosis 1;   Neurofibromatosis Type 1;   NF 1;   Neurofibroma, Plexiform
Intervention: Drug: AZD6244
18 Recruiting Natural History Study of Patients With Neurofibromatosis Type I
Conditions: Neurofibromatosis Type 1;   Malignant Peripheral Nerve Sheath Tumor;   Plexiform Neurofibroma;   Optic Glioma;   Neurofibroma
Intervention:
19 Not yet recruiting Selumetinib in Treating Patients With Neurofibromatosis Type 1 and Dermal Neurofibroma
Conditions: Appearance Distress;   Bothered by Itching Skin;   Cafe Au Lait Spot;   Cutaneous Neurofibroma;   Disfigurement;   Dysplasia;   Lisch Nodule;   Neurofibromatosis Type 1;   NF1 Gene Mutation;   Optic Nerve Glioma
Interventions: Other: Laboratory Biomarker Analysis;   Drug: Selumetinib
20 Recruiting Neurofibromatosis (NF) Registry Portal
Conditions: Neurofibromatosis 1;   Neurofibromatosis 2;   Schwannomatosis
Intervention:

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Study has passed its completion date and status has not been verified in more than two years.