COVID-19 in Patients With Anosmia in Egypt
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|ClinicalTrials.gov Identifier: NCT04473157|
Recruitment Status : Completed
First Posted : July 16, 2020
Last Update Posted : January 15, 2021
|Condition or disease|
|Anosmia Covid19 Dysgeusia|
Fifty Patients presenting to Triage and/or Ear, Nose and Throat (ENT) clinics in Ain Shams University Hospitals with the chief complaint of Anosmia/ dysgeusia in the period July- September 2020; will undergo thorough history taking, clinical assessment and polymers chain reaction rt-PCR to SARS-COV2; and if proven negative to COVID 19, PCR to other respiratory pathogens will be tested. COVID-19 patients will be managed according to the standard protocol of Ain Shams University Hospitals. Follow up after 3 weeks for the outcome of recovery of the smell sense and seroconversion by rapid test for immunoglobulins IgM/ IgG of COVID 19, for the probability of a false negative PCR at initial visit.
Ethical committee approval for the current study protocol was obtained. Patients will be invited to participate and the informed consent will be signed.
|Study Type :||Observational|
|Actual Enrollment :||58 participants|
|Official Title:||Detection of SARS-CoV-2 in Patients Presenting With Anosmia During COVID-19 Pandemic Era in Egypt|
|Actual Study Start Date :||July 1, 2020|
|Actual Primary Completion Date :||November 30, 2020|
|Actual Study Completion Date :||December 30, 2020|
- Recovery from Anosmia [ Time Frame: 3 weeks ]subjective questionnaire about smell and taste
- Seroconversion [ Time Frame: 3 weeks ]developing IgM/ IgG antibodies by rapid test
- COVID 19 [ Time Frame: 3 weeks ]developing other symptoms of COVID 19
Biospecimen Retention: Samples Without DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04473157
|Ain Shams University|
|Principal Investigator:||Ossama I Mansour, MD||Ain Shams University|