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Analysis of Human to Human Transmission of Middle East Respiratory Syndrom Coronavirus (MER-CoV) (MKU)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT02605109
Recruitment Status : Completed
First Posted : November 16, 2015
Last Update Posted : September 1, 2016
Sponsor:
Information provided by (Responsible Party):
Sang O, Park, Konkuk University Medical Center

Study Description
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Brief Summary:
This study aimed to analysis the characteristics of MERS transmission and the effect of our institutional personal protective equipment on the controlling the MERS at a tertiary Korean Hospital.

Condition or disease Intervention/treatment
Viral Infection Other: Risk of MERS infection

Detailed Description:

Between May 2015 and Nov 2015, total 186 cases of MERS-Cov infections were reported in South Korea. In June 2015, a female patient visited our emergency department (ED) for care of femur fracture. She was suspected of having MERS-Cov and isolated after 10 hours from the visit of our hospital because her clinical feature was not concordance with typical MERS-Cov infection and she denied the any contact of MERS-Cov patient. Before the transport to the isolation room, she stayed at ED during 8 hours, and admitted the general ward during 2 hours. Approximately 150 including the healthcare providers, patients and laypersons were exposed to the case-patient directly or indirectly. The investigators monitored all possible contacts in the hospital during that time, and analysed the CCTV data of hospital and interviewed all risk-persons. After the hospital outbreak ended, The investigators analysed the data of all behavior and contact history of MERS patient, epidermic and clinical data of infected patients and data of personal protective equipments (PPE) of all exposed persons.

Descriptive analysis were conducted for basic epidemiology, transmission rout of MERS in hospital, and the effect of hospital infection control system and PPE of each contacts.

Study Design
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Study Type : Observational
Actual Enrollment : 200 participants
Observational Model: Case-Control
Time Perspective: Retrospective
Official Title: Analysis of Human to Human Transmission of Middle East Respiratory Syndrom Coronavirus (MER-CoV) and Infection Control Experiences in a Medical Institution of South Korea
Study Start Date : June 2015
Actual Primary Completion Date : November 2015
Actual Study Completion Date : November 2015
Groups and Cohorts
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Group/Cohort Intervention/treatment
RiskMERS
Exposed to case-patients
 Other: Risk of MERS infection
HCPs, patients and layperson to closely or indirectly contact a case-patients


Outcome Measures
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Primary Outcome Measures :
  1. Numbers of infected patient [ Time Frame: Serologic confimred MERS case within 4 weeks after contacting to a case patients ]

Eligibility Criteria
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Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
pesons who had the risk of MERS transmission from the case-patient
Criteria

Inclusion Criteria:

  • All aged persons who have risk of MERS transmission from a case-patients

Exclusion Criteria:

  • No risk of transmission
Contacts and Locations
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Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02605109


Sponsors and Collaborators
Konkuk University Medical Center
Investigators
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Study Director: Hyun Kyun Ki, MD Devision of Infection, Department of Medicine, School of Medicine, Konkuk University, Seoul 143-729, Korea
More Information
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Publications of Results:

Other Publications:

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):

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Responsible Party: Sang O, Park, Assistant Professor, Konkuk University Medical Center
ClinicalTrials.gov Identifier: NCT02605109    
Other Study ID Numbers: MERSKORKUH
First Posted: November 16, 2015    Key Record Dates
Last Update Posted: September 1, 2016
Last Verified: August 2016
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: Undecided
Keywords provided by Sang O, Park, Konkuk University Medical Center:
MERS-CoV
Infection control
Case-control studies
Additional relevant MeSH terms:
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Infections
Virus Diseases