Locally Delivered Aloe Vera Gel in the Treatment of Chronic Periodontitis Patients With Diabetes Mellitus
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT02437747|
Recruitment Status : Completed
First Posted : May 8, 2015
Last Update Posted : May 8, 2015
|Condition or disease||Intervention/treatment||Phase|
|Diabetes Mellitus Chronic Periodontitis||Drug: SRP + Aloe Procedure: SRP||Phase 4|
Aloe vera gel was locally delivered in the periodontal pockets of ≥ 5mm bilaterally in chronic periodontitis patients with diabetes under control.(HbA1c-6.6-8.6%).The study design had two groups-one in which scaling and root planing and local delivery of aloe vera gel and the other only scaling and root planing.
The evaluation of clinical parameters of PI, GI, PPD and RAL at baseline, 6 weeks and 3 months.
HbA1c evaluated at baseline and 3 months.
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||15 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Double (Participant, Investigator)|
|Official Title:||Local Drug Delivery of Aloe Vera Gel in Chronic Periodontitis Patients With Controlled Diabetes Mellitus|
|Study Start Date :||June 2014|
|Actual Primary Completion Date :||March 2015|
|Actual Study Completion Date :||March 2015|
Experimental: SRP+ Aloe Group
Scaling and root planing was done along with application of aloe vera gel as an adjunct in selected sites.
Drug: SRP + Aloe
Scaling and root planing along with aloe vera application was done
Other Name: Korphad Ghar
Sham Comparator: SRP Group
Only scaling and root planing was done on the opposite side.
Scaling and root planing was done
- Clinical parameter of probing pocket depth [ Time Frame: 3 months ]Clinically change in the probing pocket depth.
- Glycosylated haemoglobin [ Time Frame: 3 months ]HbA1c levels evaluated at baseline and 3 months
- Clinical parameter of plaque index [ Time Frame: 3 months ]Change in the plaque index.
- Clinical parameter of gingival index [ Time Frame: 3 months ]Change in the gingival index.
- Clinical parameter of relative attachment level [ Time Frame: 3 months ]Change in the relative attachment level.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02437747
|Study Director:||Archana Singh, MDS||Dr.D.Y.Patil Vidyapeeth|