Aspirin Resistance Reversibility in Diabetic Patients (ARRDM)
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT01935193|
Recruitment Status : Unknown
Verified August 2013 by Marta Bisi, Azienda Ospedaliera San Giovanni Battista.
Recruitment status was: Recruiting
First Posted : September 5, 2013
Last Update Posted : September 5, 2013
|Condition or disease||Intervention/treatment||Phase|
|Aspirin Resistance||Drug: lysine acetylsalicylate||Phase 4|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||160 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Impact of Different Pharmacological Formulations on Aspirin Resistance Reversibility in Diabetics Patients|
|Study Start Date :||November 2011|
|Actual Primary Completion Date :||August 2013|
Experimental: asa resistant
asa resistant patients receive endovenous infusion of lysine acetylsalicylate 288 mg and if asa resistance has been reversed they have been prescribed oral soluble salt of lysine acetylsalicylate.
Drug: lysine acetylsalicylate
- platelets aggregation assessed by two tests (PFA100 and VerifyNow) [ Time Frame: 24 hours ]diabetic patients found aspirin resistant receive and infusion of 288 mg of lysine acetylsalicylate and they are tested again 24 h after the infusion to investigate if aspirin resistance have been reversed.
- stability of aggregation state after the reversion of aspirin resistance using oral formulation of lysine acetylsalicylate [ Time Frame: 1 month ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01935193
|Contact: Marta Bisi, MDemail@example.com|
|San Giovanni Battista Hospital||Recruiting|
|Contact: Marta Bisi, MD +393476985414 firstname.lastname@example.org|