Effect of Probiotics Containing Yogurts on the Composition of Biofilms in Patients Under Orthodontic Treatment
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|ClinicalTrials.gov Identifier: NCT01657539|
Recruitment Status : Completed
First Posted : August 6, 2012
Last Update Posted : September 18, 2013
|Condition or disease||Intervention/treatment||Phase|
|Dental Caries Oral Health||Dietary Supplement: Yogurt containing probiotics Dietary Supplement: Placebo yogurt||Phase 2 Phase 3|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||30 participants|
|Intervention Model:||Crossover Assignment|
|Masking:||Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)|
|Official Title:||Effects of Yogurt Containing Bifidobacterium Animalis Ssp. Lactis dn- 1173010 Probiotics in the Composition of Biofilms and Saliva of Orthodontic Patients: a Crossover, Double-blind, Randomized and Placebo Controlled Clinical Trial.|
|Study Start Date :||August 2011|
|Actual Primary Completion Date :||August 2012|
|Actual Study Completion Date :||March 2013|
Group of patients using yogurt containing probiotics during the experimental phase of the study.
Dietary Supplement: Yogurt containing probiotics
patients assigned to this group will use a yogurt containing Bifidobacterium animalis once a day during 14 days before evaluation of the outcomes.
Other Name: yogurt containing Bifidobacterium animalis
Placebo Comparator: Control Yogurt
Group of patients that will use a placebo yogurt for providing comparison with the experimental group.
Dietary Supplement: Placebo yogurt
Patients will use a yogurt without probiotics once a day during 14 days before evaluation of outcomes
Other Name: Yogurt without probiotics
- Cariogenic bacteria reduction [ Time Frame: 14 days ]The amount of cariogenic bacteria (mutans streptococci and lactobacilli) will be evaluated before and after the treatments for each patient
- Patient discomfort with the treatment [ Time Frame: 14 days after intervention ]Patients were interviewed regarding any discomfort on the use of the treatments
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01657539
|Graduate Program in Dentistry, Federal University of Pelotas|
|Pelotas, RS, Brazil, 96015560|
|Study Chair:||Maximiliano S Cenci, PhD||Graduate Program in Dentistry, Federal University of Pelotas|
|Principal Investigator:||Gabriela S Pinto, MSc||Graduate Program in Dentistry, Federal University of Pelotas|