Transversus Abdominis Plane Block and Postoperative Pain After Laparoscopic Cholecystectomy
![]() |
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. |
ClinicalTrials.gov Identifier: NCT01595165 |
Recruitment Status : Unknown
Verified July 2012 by Kim Sang-Hyun, Soonchunhyang University Hospital.
Recruitment status was: Recruiting
First Posted : May 9, 2012
Last Update Posted : July 9, 2012
|
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
Condition or disease | Intervention/treatment | Phase |
---|---|---|
Laparoscopic Cholecystectomy Postoperative Pain Abdominal Muscles Nerve Block | Procedure: Ultrasound guided subcostal TAP block Procedure: Placebo Ultrasound guided subcostal TAP block | Not Applicable |
Study Type : | Interventional (Clinical Trial) |
Estimated Enrollment : | 50 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor) |
Primary Purpose: | Treatment |
Official Title: | Effect of Subcostal Transversus Abdominis Plane Block on Early Postoperative Pain in Laparoscopic Cholecystectomy: Randomized, Controlled Trial |
Study Start Date : | July 2012 |
Estimated Primary Completion Date : | December 2012 |
Estimated Study Completion Date : | March 2013 |
Arm | Intervention/treatment |
---|---|
Placebo Comparator: Control
Control group receiving saline instead of ropivacaine
|
Procedure: Placebo Ultrasound guided subcostal TAP block
Under ultrasound guidance saline 10 ml will be injected between rectus abdominis and transverse abdominis and same study solution will be injected at subcostal transversus abdominis plane. This block will be done bilaterally. |
Experimental: TAP
TAP group receiving ropivacaine total of 150 mg at TAP under US
|
Procedure: Ultrasound guided subcostal TAP block
Under ultrasound guidance0.375% ropivacaine 10 ml will be injected between rectus abdominis and transverse abdominis and same study solution will be injected at subcostal transversus abdominis plane. This block will be done bilaterally. |
- Numerical Rating Scale (NRS) 15 min after entering recovery room [ Time Frame: 15 min after entering recovery room ]
- Fentanyl consumption at recovery room [ Time Frame: Up to 3 hours until discharge from recovery room ]
- Recovery room stay [ Time Frame: Up to 3 hours from entering recovery room to discharge ]
- Incidence of postoperative nausea and vomiting (PONV) [ Time Frame: Up to 3 hours during recovery room stay ]
- NRS at 4h, 24h, and 48 h after surgery [ Time Frame: 4h, 24h, and 48 h after surgery ]

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study: | 20 Years to 65 Years (Adult, Older Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- ASA I-II
- Age 20-65 patients scheduled elective laparoscopic cholecystectomy
Exclusion Criteria:
- Patient refusal
- Allergy to ropivacaine
- Coagulopathy
- Morbid obesity (BMI>35 kg/m2)
- Previous abdominal surgery.

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01595165
Contact: Sang-Hyun Kim, M.D., Ph.D. | 82-32-621-5328 | skim@schmc.ac.kr |
Korea, Republic of | |
Sang-Hyun Kim | Recruiting |
Bucheon, Gyeonggi, Korea, Republic of, 420767 | |
Contact: Sang-Hyun Kim, M.D., Ph.D. 82-32-621-5328 skim@schmc.ac.kr |
Principal Investigator: | Sang-Hyun Kim, M.D., Ph.D. | Soonchunhyang University Hospital |
Responsible Party: | Kim Sang-Hyun, Associate professor, Soonchunhyang University Hospital |
ClinicalTrials.gov Identifier: | NCT01595165 |
Other Study ID Numbers: |
schbcanesthesia |
First Posted: | May 9, 2012 Key Record Dates |
Last Update Posted: | July 9, 2012 |
Last Verified: | July 2012 |
laparoscopic cholecystectomy ultrasound transversus abdominis plane block |
Pain, Postoperative Postoperative Complications Pathologic Processes Pain Neurologic Manifestations |