Comparison of Two Methods of Securing Skin Grafts Using Negative Pressure Wound Therapy: Vacuum Assisted Closure (VAC) and Gauze Suction (GSUC)
The purpose of this study is to compare how well two methods (VAC and G-SUC) of securing skin grafts using negative pressure wound therapy work. Negative pressure wound therapy is a commonly used method of applying suction on wounds to remove fluid from wound and to promote healing. The VAC system is widely used and consists of a foam dressing and a portable computerized suction pump. The G-SUC method uses commonly available dressing supplies attached to vacuum (suction) pump located on the wall above a hospital bed. The investigators have frequently used both methods over the past 10 years and have not observed any specific negative side effects of either.
|Study Design:||Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind (Investigator)
Primary Purpose: Treatment
|Official Title:||Comparison of Two Methods of Securing Skin Grafts Using Negative Pressure Wound Therapy: VAC and GSUC|
- Percentage of Wounds With Complete Skin Graft Take [ Time Frame: Day 4 or 5 ] [ Designated as safety issue: Yes ]For each wound, the percentage of the skin graft that took by Day 4 or 5 was calculated. Complete take is defined as 100% take or skin graft incorporation.
- Percentage of Wounds With Total Skin Graft Loss [ Time Frame: Day 4 or 5 ] [ Designated as safety issue: No ]For each wound, whether there was total skin graft loss by Day 4 or 5 was determined.
|Study Start Date:||May 2009|
|Study Completion Date:||July 2012|
|Primary Completion Date:||December 2011 (Final data collection date for primary outcome measure)|
Gauze-based wall suction negative pressure wound therapy for 4-5 days
Gauze-based wall suction negative pressure wound therapy
Active Comparator: Vacuum-assisted closure
Vacuum-assisted closure (VAC) negative pressure wound therapy using commercially available device (KCI, Inc) for 4-5 days
Commercially available Wound VAC negative pressure wound therapy device (KCI, Inc.)
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00952120
|United States, Illinois|
|University of Chicago Medical Center, Section of Plastic and Reconstructive Surgery|
|Chicago, Illinois, United States, 60637|
|Principal Investigator:||Lawrence J Gottlieb, MD||University of Chicago, Section of Plastic and Reconstructive Surgery|