MRI in Assessing Tumor Size in Women With Ductal Carcinoma In Situ
|ClinicalTrials.gov Identifier: NCT00874458|
Recruitment Status : Completed
First Posted : April 2, 2009
Last Update Posted : November 21, 2014
RATIONALE: Diagnostic procedures, such as MRI, may help find ductal carcinoma in situ and find out how far the disease has spread.
PURPOSE: This clinical trial is studying how well MRI works in assessing tumor size in women with ductal carcinoma in situ.
|Condition or disease||Intervention/treatment|
|Breast Cancer||Procedure: magnetic resonance imaging Procedure: radiomammography Procedure: ultrasound imaging|
- Assess the contribution of MRI in accurately determining tumor size in women with ductal breast carcinoma in situ (DCIS).
- Evaluate the sensitivity of MRI in detecting DCIS.
- Evaluate the contribution of mammography in accurately determining tumor size.
- Compare the contribution of MRI vs mammography in assessing tumor extension.
- Compare the contribution of MRI vs mammography in assessing dense breasts.
- Evaluate the morphology of DCIS by MRI.
- Evaluate the curve of dynamic MRI in assessing DCIS.
- Evaluate the impact of nuclear grade of DCIS by MRI.
- Evaluate the rate of revision surgery.
OUTLINE: Patients undergo clinical examination, mammography, ultrasound imaging, unilateral breast MRI, and tissue sampling.
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||40 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Ductal Carcinoma in Situ: Protocol Evaluating the Assessment of Extension of Disease by MRI|
|Study Start Date :||April 2007|
|Primary Completion Date :||May 2011|
|Study Completion Date :||December 2013|
|Experimental: MRI||Procedure: magnetic resonance imaging Procedure: radiomammography Procedure: ultrasound imaging|
- Correlation of tumor extension by MRI with surgical histology [ Time Frame: up to 1 year ]
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00874458
|Centre Antoine Lacassagne|
|Nice, France, 06189|
|Principal Investigator:||Claire Chapellier||Centre Antoine Lacassagne|