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The Correlations Between HPV L1-Specific Immunologic Responses in Cervical Cancer and Cervical Intraepithelial Neoplasia (CIN) Patients and Their Prognosis

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ClinicalTrials.gov Identifier: NCT00728871
Recruitment Status : Unknown
Verified August 2008 by National Taiwan University Hospital.
Recruitment status was:  Recruiting
First Posted : August 6, 2008
Last Update Posted : August 6, 2008
Sponsor:
Information provided by:
National Taiwan University Hospital

Brief Summary:

A. To investigate the relationship between serum titer of anti-HPV16 antibody and clinicopathological factors of cervical cancer patients.

B. To investigate that if the serum titer of anti-HPV16 antibody could be a prognostic factor in the cervical cancer patients.

C. To investigate the serum titer of anti-HPV16 antibody in HPV16-infected populations with various disease status such as infection only, precancerous lesion, and early and advanced cervical cancer.


Condition or disease Intervention/treatment Phase
Cervical Cancer Cervical Intraepithelial Neoplasia Procedure: peripheral blood isolation Not Applicable

  Show Detailed Description

Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 600 participants
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Basic Science
Official Title: The Correlations Between HPV L1-Specific Immunologic Responses in Cervical Cancer and CIN Patients and Their Prognosis
Study Start Date : December 2005
Estimated Primary Completion Date : January 2006
Estimated Study Completion Date : December 2011

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Cervical Cancer
U.S. FDA Resources


Intervention Details:
    Procedure: peripheral blood isolation
    To isolate serum from patient peripheral blood to test the titer of HPV infection and cytokine expression


Primary Outcome Measures :
  1. overall survival [ Time Frame: from CS operation to close ]


Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  1. cervical intrapeithelial neoplasm
  2. Cervical cancer

Exclusion Criteria:


Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00728871


Contacts
Contact: Chi-An Chen, MD 886-2-2312-3456 ext 5166 cachen@ha.mc.ntu.edu.tw

Locations
China, Taiwan
Natioanal Taiwan Univ. Hospital Recruiting
Taipei, Taiwan, China, 100
Contact: Chi-An Chen, MD    886-2-2312-3456 ext 5166    cachen@ha.mc.ntu.edu.tw   
Sponsors and Collaborators
National Taiwan University Hospital
Investigators
Study Chair: Chi-An Chen, MD National Taiwan University Hospital
Study Chair: Chi-An Chen, MD National Taiwan Univ. Hosp.

Responsible Party: Chi-An Chen/Professor, National Taiwan Unviersity Hospital
ClinicalTrials.gov Identifier: NCT00728871     History of Changes
Other Study ID Numbers: 9461700838
First Posted: August 6, 2008    Key Record Dates
Last Update Posted: August 6, 2008
Last Verified: August 2008

Keywords provided by National Taiwan University Hospital:
cervical cancer, HPV, immunity

Additional relevant MeSH terms:
Uterine Cervical Neoplasms
Neoplasms
Carcinoma in Situ
Cervical Intraepithelial Neoplasia
Uterine Neoplasms
Genital Neoplasms, Female
Urogenital Neoplasms
Neoplasms by Site
Uterine Cervical Diseases
Uterine Diseases
Genital Diseases, Female
Carcinoma
Neoplasms, Glandular and Epithelial
Neoplasms by Histologic Type