Autologous Bone Marrow Transplanted Via Transendocardial Catheter to Chronic Myocardial Infarct Border Zone (TABMMI)
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|ClinicalTrials.gov Identifier: NCT00507468|
Recruitment Status : Completed
First Posted : July 26, 2007
Last Update Posted : November 3, 2009
The object of this open-labeled, uncontrolled pilot study was to investigate the safety and feasibility of percutaneously transplanting autologous bone marrow (ABM) cells into the myocardium using the helical needle transendocardial (TE) delivery system in stable coronary patients with ventricular dysfunction due to chronic myocardial infarction (MI).
A secondary goal was to assess the possibility that such cell injections could improve ejection fraction (EF).
|Condition or disease||Intervention/treatment||Phase|
|Ventricular Dysfunction Myocardial Infarction||Procedure: Transendocaridal Transplantation of Autologous Bone Marrow||Phase 1|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||20 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Autologous Bone Marrow Transplanted Via Transendocardial Catheter to Chronic Myocardial Infarct Border Zone|
|Study Start Date :||December 2005|
|Actual Primary Completion Date :||March 2009|
|Actual Study Completion Date :||August 2009|
- Procedure: Transendocaridal Transplantation of Autologous Bone Marrow
Single treatment, harvest and transplant of patients own bone marrow. Cells are delivered to the myocardium via transendocardial delivery catheter.
- Safety of treatment [ Time Frame: 6 months ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00507468
|Buenos Aires, Argentina, 1118|
|Argentine Institute of Diagnosis and Treatment|
|Buenos Aires, Argentina, 1122|
|Principal Investigator:||Luis de la Fuente, MD||Argentine Institute of Diagnosis and Treatment|