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The Effectiveness of Idazoxan in Treating TRD

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ClinicalTrials.gov Identifier: NCT00294944
Recruitment Status : Withdrawn
First Posted : February 22, 2006
Last Update Posted : January 29, 2008
Sponsor:
Information provided by:
Sheba Medical Center

Brief Summary:
Assessing the effectiveness of Idazoxan as a treatment for depressive patients who did not respond to treatment with SSRI

Condition or disease Intervention/treatment Phase
Major Depressive Disorder Drug: Idazoxan Phase 3

Study Type : Interventional  (Clinical Trial)
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double

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Ages Eligible for Study:   18 Years to 65 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Criteria

Inclusion Criteria:

  • MDD patients
  • Did not respond to at least one treatment of 4-6 weeks of SSRI in adequate dose
  • In or out patients

Exclusion Criteria:

  • Psychotic symptoms

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To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00294944


Locations
Israel
Chaim Sheba Medical Center
Ramat-Gan, Israel, 52621
Sponsors and Collaborators
Sheba Medical Center
Investigators
Principal Investigator: Joseph Zohar, MD Sheba Medical Center

Responsible Party: Prof. Joseph Zohar, Chaim Sheba Medical Center
ClinicalTrials.gov Identifier: NCT00294944     History of Changes
Other Study ID Numbers: SHEBA-05-3911-JZ-CTIL
First Posted: February 22, 2006    Key Record Dates
Last Update Posted: January 29, 2008
Last Verified: January 2008

Additional relevant MeSH terms:
Depressive Disorder
Depression
Depressive Disorder, Major
Mood Disorders
Mental Disorders
Behavioral Symptoms
Idazoxan
Adrenergic alpha-2 Receptor Antagonists
Adrenergic alpha-Antagonists
Adrenergic Antagonists
Adrenergic Agents
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action
Physiological Effects of Drugs