Alfimeprase for Thrombolysis in Acute Peripheral Arterial Occlusion
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The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. |
ClinicalTrials.gov Identifier: NCT00073554 |
Recruitment Status :
Completed
First Posted : November 26, 2003
Last Update Posted : December 17, 2009
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Condition or disease | Intervention/treatment | Phase |
---|---|---|
Arterial Occlusive Diseases Peripheral Vascular Diseases Thrombosis | Drug: Alfimeprase | Phase 2 |
Study Type : | Interventional (Clinical Trial) |
Enrollment : | 100 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | None (Open Label) |
Primary Purpose: | Treatment |
Official Title: | A Phase 2, Multicenter, Open-Label, Dose-Escalation Study to Evaluate the Safety and Activity of Alfimeprase in Patients With Acute Peripheral Arterial Occlusion |
Study Start Date : | June 2003 |

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Ages Eligible for Study: | 18 Years and older (Adult, Older Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
- Patients with acute peripheral arterial occlusion of the lower limb (onset of symptoms within 14 days)
- Rutherford Class I or IIa (minimal sensory loss, no muscle weakness, audible venous flow)
- Age 18 or above
- Able to consent
- Able to follow up

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00073554
United States, Ohio | |
Cleveland Clinic Foundation | |
Cleveland, Ohio, United States |
ClinicalTrials.gov Identifier: | NCT00073554 |
Other Study ID Numbers: |
HA002 NAPA-1 |
First Posted: | November 26, 2003 Key Record Dates |
Last Update Posted: | December 17, 2009 |
Last Verified: | November 2006 |
Thrombosis Vascular Diseases Peripheral Vascular Diseases Peripheral Arterial Disease Arterial Occlusive Diseases |
Embolism and Thrombosis Cardiovascular Diseases Atherosclerosis Arteriosclerosis |