Drug Treatment for Pathological Gambling

This study has been completed.
Information provided by:
University of Iowa
ClinicalTrials.gov Identifier:
First received: February 28, 2003
Last updated: July 25, 2013
Last verified: July 2013

This study will determine whether the drug bupropion is an effective treatment for Pathological Gambling.

Condition Intervention
Drug: Bupropion

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double-Blind
Primary Purpose: Treatment
Official Title: Bupropion Versus Placebo in the Treatment of Pathological Gambling

Resource links provided by NLM:

Further study details as provided by University of Iowa:

Estimated Enrollment: 80
Study Start Date: July 2002
Study Completion Date: April 2006
Primary Completion Date: May 2005 (Final data collection date for primary outcome measure)
Detailed Description:

As gambling opportunities proliferate, PG has become a major health concern. Despite its importance, few treatment options with proven efficacy exist. This study will attempt to identify an effective treatment for PG.

Participants are randomly assigned to receive either bupropion or placebo for 12 weeks. Participants are assessed at baseline and at Weeks 2, 3, 4, 5, 6, 8, 10, and 12. Self administered questionnaires and interviews are used to assess participants. Follow-up assessments are made 1, 3, and 6 months after study completion.


Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • PG for at least 1 year
  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00055393

United States, Iowa
Roy J. and Lucille A. Carver College of Medicine, University of Iowa
Iowa City, Iowa, United States, 52242
Sponsors and Collaborators
University of Iowa
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00055393     History of Changes
Other Study ID Numbers: R21 MH63289, R21MH063289, DSIR AT-AS
Study First Received: February 28, 2003
Last Updated: July 25, 2013
Health Authority: United States: Federal Government

Additional relevant MeSH terms:
Impulse Control Disorders
Mental Disorders

ClinicalTrials.gov processed this record on March 26, 2015