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To determine cell cycle parameters and changes after treatment, the labelling agent is given and a bone marrow aspiration is accomplished before treatment and after treatment for comparison. Participants must be undergoing concurrent therapy for hematologic malignancy.
Condition or disease
Drug: Chemotherapy for hematologic malignancy
Cell cycle parameters include LI, Ts, Tc, T dpot, changes in these parameters, and differences between normal and leukemic cells in patients with hematologic malignancy prior to and following treatment.
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Ages Eligible for Study:
18 Years and older (Adult, Senior)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Histologic proof of one of:
AML, ALL, or AUL
MDS or CMML
OR undergoing bone marrow transplantation.
Participants should be:
off therapy for at least two weeks
At least 18 years old or older
Using adequate contraception if of child-bearing capability.