Prone Position During ECMO in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Hypoxaemic Patient
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT04995289|
Recruitment Status : Completed
First Posted : August 6, 2021
Last Update Posted : August 13, 2021
The main manifestation of COVID-19 pneumonia is acute respiratory distress syndrome (ARDS), which in some cases can be more severe than intubation, extracorporeal membrane venous oxygenation (VV-ECMO) to ensure hematosis. Despite support from VV-ECMO, some patients may remain hypoxemic. One possible therapeutic procedure for these patients is the application of the prone position.
The main aim of this study was to investigate the modification of the PaO2/FiO2 ratio, the compliance of the respiratory system in VV-ECMO with refractory hypoxemia. The secondary objective was to evaluate the safety and feasibility of the inclined position for ECMO.
the investigators reviewed the electronic records and lists of all 23 COVID-19 patients. were placed for the first time in PP with an average duration of 16 h . patient characteristics, pre-ECMO characteristics, ventilator/ECMO settings, and changes in ventilator/ECMO settings and blood gas analysis before and after PP.
|Condition or disease||Intervention/treatment|
|SARS CoV 2 Infection Hypoxemic Respiratory Failure||Other: Prone position on ECMO patient|
The main objective of the current study was to investigate the change in PaO2/FiO2 ratio, the compliance of the respiratory system in VV-ECMO patients with persistent hypoxemia. Measurements were taken before PP, 1 h after the start of the PP, at the end of the PP cycle.
The secondary objective of this study was to assess the safety and feasibility of emergency positioning for patients with severe ARDS during ECMO treatment.
|Study Type :||Observational|
|Actual Enrollment :||23 participants|
|Official Title:||Prone Position During ECMO in Covid Hypoxaemic Patient :A PROCESS-compliant Case Series From the Eastern Morocco|
|Actual Study Start Date :||January 1, 2020|
|Actual Primary Completion Date :||January 30, 2021|
|Actual Study Completion Date :||January 30, 2021|
- Other: Prone position on ECMO patient
blood gas analysis before and after PP
- amelioration of PaO2/FiO2 [ Time Frame: through study completion, an average of 1 yea ]the investigators recoordeed Blood gas analysis before and after Prone position
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04995289
|Berkane, Morocco, 9999|