Topical Steroids and Cyclosporin-A for COVID-19 Keratoconjunctivitis
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|ClinicalTrials.gov Identifier: NCT04451239|
Recruitment Status : Unknown
Verified June 2020 by Ameera Gamal Abdelhameed, Mansoura University.
Recruitment status was: Not yet recruiting
First Posted : June 30, 2020
Last Update Posted : June 30, 2020
|Condition or disease||Intervention/treatment||Phase|
|Keratonjunctivitis||Drug: topical steroids and cyclosporin-A||Not Applicable|
COVID-19 patients presenting with acute keratoconjunctivitis will be treated with Topical 1% prednisolone acetate fourTimes daily for 7 days as initial treatment, non-preserved artificial tears four times daily and cyclosporin A 0.5% four times daily .
Twelve patients with COVID-19 Keratoconjunctivitis will be enrolled in this open-label study. Symptoms and findings of the patients before and after treatment were recorded.
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||12 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Combined Topical Corticosteroid and Topical Cyclosporine-A for Management of COVID-19 Keratoconjunctivitis; a Pilot Study|
|Estimated Study Start Date :||June 30, 2020|
|Estimated Primary Completion Date :||July 2020|
|Estimated Study Completion Date :||July 2020|
cases will receive topical 1% prednisolone acetate for 7 days as initial treatment +non-preserved artificial tears and cyclosporin A 0.5% four times daily .
Drug: topical steroids and cyclosporin-A
All patient will be treated with Topical 1% prednisolone acetate for 7 days as initial treatment +non-preserved artificial tears and cyclosporin A 0.5% four times daily .
- Symptom improvement [ Time Frame: 10-15 days ]eye itching, foreign body sensation, tearing, redness in the eye and eyelid swelling
- Signs improvement [ Time Frame: 10-15 days ]conjunctival injection, discharge, presence of superficial punctate keratitis (SPK), pseudomembranes on tarsal conjunctiva
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04451239
|Contact: Ameera Abdelhameed, MDfirstname.lastname@example.org|
|Kuwait, Farawanyia, Kuwait|
|Contact: Mona Nasseif, MD 96566578919 Monanasseif@gmail.com|
|Principal Investigator:||Mona Nasseif, MD||Tanta University|