Wells and Enteric Disease Transmission Trial (WET - Trial)
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT04258059|
Recruitment Status : Recruiting
First Posted : February 6, 2020
Last Update Posted : February 24, 2020
|Condition or disease||Intervention/treatment||Phase|
|Gastrointestinal Infection Respiratory Viral Infection||Device: Active household UV water treatment device Device: Inactive household UV water treatment device||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||30 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Triple (Participant, Investigator, Outcomes Assessor)|
|Official Title:||Wells and Enteric Disease Transmission - A Randomized Controlled Trial (WET- Trial)|
|Actual Study Start Date :||December 16, 2019|
|Estimated Primary Completion Date :||June 2021|
|Estimated Study Completion Date :||September 2021|
Active Comparator: Active UV Device
A household water treatment device with a lamp emitting germicidal UV. The device will be operated at 50 millijoule per square centimeter to treat >99.9% of all bacteria, protozoa, and most viruses in water supplies.
Device: Active household UV water treatment device
This point-of-entry treatment device will use germicidal UV to treat all of the well water used in the home.
Sham Comparator: Inactive UV Device
A device that appears identical to the active comparator device except the lamp will not emit germicidal UV.
Device: Inactive household UV water treatment device
This sham device will use a lamp not emitting germicidal UV.
- Incident gastrointestinal illness [ Time Frame: 12 months ]The investigators will collect data on the presence of gastrointestinal illness symptoms through weekly text messages. Households that report symptoms through text messages will be directed to an online illness questionnaire to characterize the symptoms (incidence, severity, duration, diarrhea, vomiting, coughing, etc.), febrile episodes, as well as relevant exposure information such as recent travel, exposure to ill persons, etc. Incident gastrointestinal illness (GI) is defined by the reporting of a minimum of three episodes of diarrhea or vomiting in a 24 hour period. Each illness will be considered distinct when separated by ≥ 6 symptom-free days.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04258059
|Contact: Heather Murphy, PhDemail@example.com|
|United States, Pennsylvania|
|Philadelphia, Pennsylvania, United States, 19122|
|Contact: Heather M Murphy, PhD 215-204-4766 firstname.lastname@example.org|
|Contact: Debbie Lee, PhD 215-204-5124 email@example.com|
|Principal Investigator: Heather M Murphy, PhD|
|Principal Investigator:||Heather Murphy, PhD||Assistant Professor|