Orthognathic Speech Pathology: Phonetic Contrasts of Patients With Dental Discrepancies Pre- and Post-Treatment Analyses (OSP)
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|ClinicalTrials.gov Identifier: NCT04117360|
Recruitment Status : Recruiting
First Posted : October 7, 2019
Last Update Posted : October 7, 2019
|Condition or disease||Intervention/treatment|
|Dentofacial Abnormalities Dentofacial Deformities Dentofacial Anomalies, Including Malocclusion Malocclusion Malocclusion in Children Dentofacial Disharmony Skeletal Malocclusion Skeletal Malformation Speech Sound Disorder Speech Disorders||Other: Orthognathic surgery and Orthodontics|
Purpose: The investigators are studying how phoneme distortion is effected by jaw disproportions in dentofacial disharmony (DFD) patients and whether speech improves after orthognathic surgery and orthodontic treatment. Spectral moment and tongue gestural analysis are being used to mechanistically determine how jaw position effects speech. The investigators hypothesize that skeletal open and underbites contribute to phoneme distortion and tongue gestural changes that improve following surgical correction of jaw position. All DFD patients are already seeking treatment from orthodontics and oral surgery. The study will observe how their speech changes before and after treatment. There is no randomization or intervention involved.
Aim 1: Qualify the prevalence of auditory and visual speech distortions in the DFD population. Aim 2: Quantitatively evaluate the first spectral moment (kHz) of four articulating consonant sounds (/t/, /k/, /s/, and /?/ pronounced "sh"). Quantify and analyze the changes in speech distortions for orthognathic patients pre and post-operation. Aim 3: Evaluate tongue posture during speech with patients from Aim 2 pre and post-operation.
Participants: Patients of the UNC dentofacial disharmony (DFD) clinic who have undergone orthognathic surgery for correction of jaw disharmonies.
Patients will be recorded pronouncing a series of words highlighting a range of phonetic contrasts including --/s-sh/ and t-k/. words each presented on a screen using PowerPoint, 3 times each with carrier phrases). Recordings include an acoustic feed, a profile video of the jaws plus lips, and ultrasound imaging of the tongue relative to the palate and jaws. Research staff will score audio recordings according to their spectral moments and ultrasound recordings according to tongue movement and associate findings with degree of dental discrepancy. Prospective recordings will be collected at three timepoints: 1-3 months prior to jaw surgery, 3-8 months and 9-15 months post-operation for 60 overbite, 60 openbite and 60 underbite DFD patients. These time points were selected to co-occur with patients' surgical check-ups to ensure reliable data collection while minimizing confounding factors such as severe facial swelling and splint placement which occur immediately after surgery.
|Study Type :||Observational|
|Estimated Enrollment :||180 participants|
|Official Title:||Orthognathic Speech Pathology: Phonetic Contrasts of Patients With Dentofacial Discrepancies With Pre- and Post-Treatment Analyses|
|Estimated Study Start Date :||October 2019|
|Estimated Primary Completion Date :||December 2024|
|Estimated Study Completion Date :||December 2025|
Dentofacial Disharmony Patients
Dentofacial disharmony patients who are seeking jaw surgery in UNC oral and maxillofacial surgery department and are seen in UNC orthodontic dentofacial disharmony clinic.
Other: Orthognathic surgery and Orthodontics
This study is observational. All subjects identified to participate will be undergoing orthognathic jaw surgery and orthodontic treatment.
- Change in Speech Distortion Phonemes over Time [ Time Frame: pre-operation through 9-15 months post-operation ]Audio recordings of consonant phonemes will be quantitatively analyzed using spectral moment analysis yielding mean values.
- Change in Quantitative Tongue Gestures over Time [ Time Frame: pre-operation through 9-15 months post-operation ]Ultrasound analysis of tongue posture to quantitatively describe tongue position during speech.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04117360
|Contact: Laura A Jacox, PhD, DMD, MS||847- email@example.com|
|Contact: Sherrill T Phillips, BSfirstname.lastname@example.org|
|United States, North Carolina|
|University of North Carolina||Recruiting|
|Chapel Hill, North Carolina, United States, 27514|
|Contact: Laura A Jacox, DMD, PhD, MS 847-702-0988 LJacox@ad.unc.edu|
|Principal Investigator: Laura A Jacox, DMD, PhD, MS|
|Principal Investigator:||Laura A Jacox, PhD, DMD, MS||Professor|