The Impact of Physical Activity on the Postoperative Symptoms, Complications, and Quality of Life Among Lung Cancer
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The purpose of this study is to examine the impact of physical activity on the postoperative symptoms, complication, and quality of life.
Condition or disease
Non-small cell lung cancer (NSCLC) survivor is increasing as developing early diagnosis and perioperative management. Despite multidisciplinary treatment, Surgery is the primary treatment option for cure in NSCLC. The patients with lung cancer who underwent surgery have limitation of pulmonary function and high risk of co-morbidities. Perioperative physical activity has been shown to reduce symptoms and prevent complications, improve long term quality of life after surgery. But validated exercise regimen has not been established for lung cancer patients. Therefore, Evidence-based guideline focusing on lung cancer after surgery is needed.
The change of quality of life: (EORTC QLQ) core30 (C30) [ Time Frame: Before surgery (baseline), and 1, 6, 12, 24, 36, 48, and 60 months after surgery ]
The change of quality of life is measured using the European Organization for Research Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ) core30 (C30). The scale for quality of life is transformed into a score from 0 to 100, derived by 4-point Likert scale. A higher score represents a higher level of quality of life.
Secondary Outcome Measures :
Postoperative pulmonary complications [ Time Frame: Within 30 days after surgery ]
Incidence of pulmonary complications including air leak, atelectasis, pleural effusion, pneumonia, etc.
The change of symptom [ Time Frame: Before surgery (baseline), and 1, 6, 12, 24, 36, 48, and 60 months after surgery ]
The change of symptom is measured using the European Organization for Research Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ) lung cancer module 13 (LC13). The scale for symptom is transformed into a score from 0 to 100, derived by 4-point Likert scale. A higher score represents a higher level of symptom.
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Layout table for eligibility information
Ages Eligible for Study:
18 Years and older (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
The study population in this study consists of patients who are diagnosed with lung cancer and scheduled for surgery in a lung cancer center at Seoul.
Patients who are diagnosed with lung cancer
Patients who are able to walk with ECOG (Eastern Cooperative Oncology Group) performance status < 1
Patients who understand the purpose of this study and provide the written informed consent
Patients who have difficulty for walking
Patients with history of other cancer in the last 3 years
Patients with neoadjuvant chemotherapy and/or radiation therapy
Patients who are diagnosed with recurrent lung cancer or multiple cancer
Foreigner of patients from overseas who are not able regularly participate in this study