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Effectiveness of Nerve Glide Exercises on Cubital Tunnel Syndrome

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details. Identifier: NCT03629470
Recruitment Status : Recruiting
First Posted : August 14, 2018
Last Update Posted : October 28, 2021
Information provided by (Responsible Party):
NYU Langone Health

Brief Summary:
The objective of this study is to determine if nerve glide exercises in patients with cubital tunnel syndrome can improve pain, paraesthesias and reduce the need for future surgery. Cubital tunnel syndrome is a common form of peripheral neuropathy caused by compression of the ulnar nerve at the elbow. Surgical intervention is typically reserved for those with severe symptoms, but many cases can be treated with non-operative measures. This study will look at the efficacy of nerve glide exercises in the management of cubital tunnel syndrome. 70 subjects with cubital tunnel syndrome will be enrolled and randomized into groups receiving either standard conservative measures or standard measures in addition to nerve glide exercises. Outcomes will be measured 6 months after initiation of treatment with questionnaires on clinical symptoms and function to see if there is a difference between the two groups.

Condition or disease Intervention/treatment Phase
Cubital Tunnel Syndrome Other: Standard Conservative Treatment Other: Nerve Gliding Exercises Phase 2

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Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 70 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Effectiveness of Nerve Glide Exercises on Cubital Tunnel Syndrome
Actual Study Start Date : November 9, 2020
Estimated Primary Completion Date : November 2022
Estimated Study Completion Date : December 2022

Arm Intervention/treatment
Active Comparator: Group 1
standard conservative treatment
Other: Standard Conservative Treatment
Range of motion exercises, medication and activity modification.

Experimental: Group 2
nerve gliding exercises along with the standard conservative treatment.
Other: Standard Conservative Treatment
Range of motion exercises, medication and activity modification.

Other: Nerve Gliding Exercises
Taught by occupational therapist. These exercises involve motions of the wrist, arm and neck. Subjects will be instructed to perform exercises regularly following the occupational therapists' protocol

Primary Outcome Measures :
  1. Clinical Scoring [ Time Frame: 1 Month ]
    30 item questionnaire used as a clinical scoring system.

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

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Ages Eligible for Study:   18 Years to 80 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Patients diagnosed with cubital tunnel syndrome on physical exam

Exclusion Criteria:

  • Patients with diagnosed or self-reported cognitive dysfunction
  • Patients who are unable to understand or follow commands
  • Any patient that the investigators feel unsafe or cannot comply with all study related procedures
  • Patients who had previous ulnar nerve release at the elbow
  • Patients with documented cervical spine pathology
  • Patients with clinical signs of other nerve pathology
  • Patients with palpable subluxation of the ulnar nerve at the elbow

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT03629470

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Contact: Karen Noh 201-518-6677

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United States, New York
New York University School of Medicine Recruiting
New York, New York, United States, 10016
Contact: Karen Noh   
Principal Investigator: Louis Catalano, MD         
Sponsors and Collaborators
NYU Langone Health
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Principal Investigator: Louis Catalano, MD NYU Langone Health
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Responsible Party: NYU Langone Health Identifier: NCT03629470    
Other Study ID Numbers: 17-01734
First Posted: August 14, 2018    Key Record Dates
Last Update Posted: October 28, 2021
Last Verified: October 2021
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Additional relevant MeSH terms:
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Cubital Tunnel Syndrome
Pathologic Processes
Ulnar Neuropathies
Peripheral Nervous System Diseases
Neuromuscular Diseases
Nervous System Diseases
Ulnar Nerve Compression Syndromes
Nerve Compression Syndromes
Cumulative Trauma Disorders
Sprains and Strains
Wounds and Injuries