Working…
ClinicalTrials.gov
ClinicalTrials.gov Menu

The Effects of a Jump Rope Exercise Program on Vascular Health, Inflammatory Markers in Prehypertensive Adolescent Girls

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT03534427
Recruitment Status : Completed
First Posted : May 23, 2018
Results First Posted : August 14, 2019
Last Update Posted : August 14, 2019
Sponsor:
Information provided by (Responsible Party):
Songyoung Park, Pusan National University

Brief Summary:
The purpose of this study was to examine the impact of a 12-week jump rope exercise program on blood pressure, arterial stiffness, vasodilating and vasoconstricting factors, inflammatory markers, and body composition in prehypertensive adolescent girls. Forty prehypertensive adolescent girls participated in this study. The girls were randomly divided into the jump rope exercise intervention group (EX, n=20) and control group (CON, n=20). The EX group performed a jump rope training program at 40-70% of their heart rate reserve (HRR) 5 days/week for 12 weeks (sessions 50 minutes in duration). The CON group did not participate in any structured or unstructured exercise protocol. Blood pressure, arterial stiffness, plasma nitrate/nitrite levels, endothelin-1, C-reactive protein, and body composition were measured before and after the 12-weeks study.

Condition or disease Intervention/treatment Phase
Prehypertension Blood Pressure Abdominal Obesity Adiposity Other: Jump rope exercise intervention Not Applicable

Layout table for study information
Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 40 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Intervention Model Description: exercise intervention group, control group
Masking: None (Open Label)
Primary Purpose: Health Services Research
Official Title: The Effects of a 12-Week Jump Rope Exercise Training Program on Arterial Stiffness, Vasodilating and Vasoconstricting Factors, Inflammatory Markers, and Body Composition in Prehypertensive Adolescent Girls
Actual Study Start Date : June 5, 2016
Actual Primary Completion Date : February 10, 2018
Actual Study Completion Date : March 21, 2018

Resource links provided by the National Library of Medicine


Arm Intervention/treatment
No Intervention: Control group
No exercise intervention
Experimental: Jump rope exercise intervention
The jump rope exercise program was performed for 50 minutes with 5 minutes of warm-up and cool-down per day, 5 times a week for 12 weeks. The program consisted of various main jump rope exercises (1 line 2 jump, jumping feet together, running jumping, open side jump, open back and forth jump, rock paper scissor jump). The warm-up and cool down consisted of static stretching, walking, and jogging. Intensity of exercise was gradually increased from 40-50% heart rate reserve (HRR) in weeks 1-4 and to 60-70% HRR in weeks 9-12. Each training session was supervised by the researchers. Every subject wore a heart rate monitor during the whole training session in order to maintain the designated training intensity.
Other: Jump rope exercise intervention
12-week jump rope exercise program




Primary Outcome Measures :
  1. Arterial Stiffness [ Time Frame: 12 weeks ]
    Arterial stiffness was measured as measurement of brachial to ankle pulse-wave velocity. This indicates peripheral arterial stiffness, as it measures how quickly a pulse wave propagates from one point to another.

  2. Endothelin-1 [ Time Frame: 12 weeks ]
    Levels of Endothelin-1 in blood were measured by Endothelin-1 enzyme immunoassay kit.

  3. Body Mass [ Time Frame: 12 weeks ]
    Body mass was measured to nearest 0.1 kg.

  4. Height [ Time Frame: 12 weeks ]
    Height was measured to nearest 1 cm.

  5. Waist Circumference [ Time Frame: 12 weeks ]
    Waist circumference was measured at midpoint between the lower rib and the iliac crest at the end of a normal expiration using a tape measure.

  6. Body Fat [ Time Frame: 12 weeks ]
    Percent body fat (%) was determined using a bioelectrical impedance-meter.

  7. Lean Body Mass [ Time Frame: 12 weeks ]
    Lean body mass (kg) was determined using a bioelectrical impedance-meter.

  8. Nitrate/Nitrite Levels [ Time Frame: 12 weeks ]
    Nitrate and nitrite levels were assayed using a Griess assay kit.

  9. C-reactive Protein [ Time Frame: 12 weeks ]
    C-reactive protein was assessed using an enzyme immunoassay assay kit

  10. Systolic Blood Pressure [ Time Frame: 12 weeks ]
    Blood pressure was measured in duplicate using an automated sphygmomanometer. The average of the two was recorded as the resting blood pressure.

  11. Diastolic Blood Pressure [ Time Frame: 12 weeks ]


Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Layout table for eligibility information
Ages Eligible for Study:   14 Years to 16 Years   (Child)
Sexes Eligible for Study:   Female
Gender Based Eligibility:   Yes
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • prehypertensive
  • sedentary (no regular exercise training or physical activity within the last year)
  • no weight loss diet during the last six months

Exclusion Criteria:

  • pregnancy
  • chronic disease
  • daily medication use (including antioxidants and weight loss supplements)
  Study Documents (Full-Text)

Documents provided by Songyoung Park, Pusan National University:

Layout table for additonal information
Responsible Party: Songyoung Park, Principal Investigator, Pusan National University
ClinicalTrials.gov Identifier: NCT03534427     History of Changes
Other Study ID Numbers: PusanNU1
First Posted: May 23, 2018    Key Record Dates
Results First Posted: August 14, 2019
Last Update Posted: August 14, 2019
Last Verified: July 2019
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

Layout table for additional information
Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Keywords provided by Songyoung Park, Pusan National University:
arterial stiffness
endothelin-1
c-reactive protein
adiposity
exercise
jump rope
Additional relevant MeSH terms:
Layout table for MeSH terms
Prehypertension
Obesity
Obesity, Abdominal
Overnutrition
Nutrition Disorders
Overweight
Body Weight
Signs and Symptoms
Vascular Diseases
Cardiovascular Diseases