The Effect of Some Parturients' Characteristics on Sensory Block Level After Spinal Anesthesia
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|ClinicalTrials.gov Identifier: NCT03164096|
Recruitment Status : Unknown
Verified January 2018 by Ghada Mohammed AboelFadl, Assiut University.
Recruitment status was: Recruiting
First Posted : May 23, 2017
Last Update Posted : March 29, 2018
|Condition or disease||Intervention/treatment||Phase|
|Anesthesia, Obstetrical||Drug: Bupivacaine Hydrochloride||Phase 4|
However, in pregnant patients, venous engorgement is prominent in the supine but not the lateral position, which suggests direct compression of the inferior vena cava by the gravid uterus. Second, an increase in intraabdominal pressure may affect the retroperitoneal area and may cause inward movement of soft tissue in the intervertebral foramina. Recent magnetic resonance imaging studies in pregnant patients, although without intraabdominal pressure measurements, suggested the latter because they showed limited contact of engorged veins along the dural sac which may therefore not be responsible for compression of the dura.
If elevated intraabdominal pressure contributes to high anesthetic spread during pregnancy, one would expect a relationship between intraabdominal pressure and maximum sensory block level.
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||100 participants|
|Intervention Model:||Single Group Assignment|
|Intervention Model Description:||evaluating relationship of sensory level and other patient factors|
|Masking:||None (Open Label)|
|Official Title:||The Effect of Body Mass Index, Intra-abdominal Pressure, Abdominal Girth and Waist Circumference on Sensory Block Level After Single-shot Spinal Anesthesia for Cesarean Section|
|Actual Study Start Date :||June 1, 2017|
|Estimated Primary Completion Date :||December 1, 2018|
|Estimated Study Completion Date :||December 10, 2018|
Experimental: intrathecal bupivacaine
intrathecal bupivacaine hydrochloride 0.5%,12.5mg
Drug: Bupivacaine Hydrochloride
intrathecal bupivacaine will be used for spinal anesthesia in obstetric patients undergoing C-section
Other Name: intrathecal bupivacaine
- sensory level [ Time Frame: from allocation until 24 hours post-operative ]effect of different parameters in sensory level
- motor block [ Time Frame: from allocation until 24 hours post-operative ]effect of different parameters in motor level
- hypotension [ Time Frame: from allocation until 24 hours post-operative ]incidence of hypotension after spinal anesthesia
- vasopressor consumption [ Time Frame: from allocation until 24 hours post-operative ]total dose of ephedrine consumed by the patients
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Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03164096
|Contact: Ghada M Aboelfadl, MD 01005802086 firstname.lastname@example.org|