Termination Therapy for Ventricular Tachyarrhythmias (JUPITER)

Inclusion Criteria:

1. Life expectancy of 1 year or greater
2. Male or female between 18 and 75 years of age
3. Willingness and ability to comply with the study protocol, including providing a written, informed consent
4. Subject indicated for a cardiac catheter ablation procedure for sustained VT/VF or non-sustained VT with associated electrophysiology study OR subject indicated for implantable cardioverter defibrillator implant or replacement that, at time of study consent, are medically stable to undergo defibrillation safety margin testing procedure performed under conscious sedation as determined by the investigator

Exclusion Criteria:

The subject must not meet any of the following exclusion criteria:

1. Medically unstable at time of study to undergo defibrillation testing
2. Hemodynamic instability as determined by the investigator
3. Prior VT ablation with history of hemodynamic compromise
4. Atrial Tachyarrhythmia (AT/AFl/AF) at time of study procedure
5. Incessant VT/VF
6. Inability to Tolerate Systemic Anticoagulation
7. LVEF < 15%
8. New York Heart Association (NYHA) Class IV
9. History of intracardiac thrombus
10. History of hyper-coagulable state that increases risk of thrombus
11. History of hemodynamic compromise severe aortic stenosis
12. Inability to Pass Catheters to Heart Due to Vascular Limitations
13. Cardiovascular anatomical defects that would complicate placement of the lead or catheter required by the protocol, including congenital heart disease and cardiac vein anomalies as determined by the investigator
14. Unstable CAD as determined by the investigator
15. Severe proximal three-vessel or left main coronary artery disease without revascularization as determined by the investigators
16. History of embolic stroke, Transient Ischemic Attack or other thromboembolic event
17. History of Hypertrophic Cardiomyopathy, or Arrhythmogenic RV Dysplasia
18. Cardiovascular surgery or intervention within 1 month prior to enrollment or planned for up to 1 month after enrollment (other than the planned treatment procedure)
19. Pregnancy confirmed by test within 7 days of procedure
20. Pacemaker Dependency
21. Morbid obesity: BMI>39 kg/m2
22. Medically unstable at time of study to undergo defibrillation testing
23. Cognitive or mental health status that would interfere with study participation and proper informed consent
24. Presence of other permanently implanted medical devices (e.g. artificial cardiac valves) that may affect the outcomes of this study or safety of the subject, as determined by the investigator (except ICD)
25. History of significant Peripheral Vascular Disease, including peripheral vascular interventions and IVC filter placement
26. Any other medical condition which may affect the outcome of this study or safety of the subject as determined by the investigator