Dental Malocclusion and Craniofacial Development in OI
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT02934451|
Recruitment Status : Active, not recruiting
First Posted : October 17, 2016
Last Update Posted : January 24, 2022
|Condition or disease|
Investigators will look at dental health in people with OI and will describe teeth misalignment and head and neck defects in individuals with moderate to severe Osteogenesis Imperfecta (OI).
Investigators will look at results from the Longitudinal study of OI to complete the study evaluations. Several x-rays will be performed for this study. Participants will have a 3D scan of the mouth and a Cone Beam CT scan of the jaw at a baseline visit and at 3 years after the baseline visit. These study visits can be at the same time as the Longitudinal Study of OI study visits.
|Study Type :||Observational|
|Actual Enrollment :||75 participants|
|Official Title:||Dental Malocclusion and Craniofacial Development in OI|
|Actual Study Start Date :||August 2016|
|Estimated Primary Completion Date :||December 2023|
|Estimated Study Completion Date :||December 2024|
- Teeth Misalignment [ Time Frame: 5 years ]Measure teeth misalignment in individuals with moderate to severe OI using scans of the teeth.
- Neck Defects [ Time Frame: 5 years ]Determine neck defects in individuals with moderate to severe OI using scans of the neck and jaw.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02934451
|United States, California|
|University of California Los Angeles|
|Los Angeles, California, United States, 90095|
|United States, Texas|
|Baylor College of Medicine|
|Houston, Texas, United States, 77030|
|Shriners Hospital for Children|
|Montreal, Quebec, Canada, H3G 1A6|
|Study Chair:||Jean-Marc Retrouvey, D.M.D.||McGill University|
|Study Chair:||Reid Sutton, M.D.||Baylor College of Medicine|
|Study Chair:||Frank Rauch, M.D.||Shriners Hospital for Children|