Does Body Positioning Affect the Yield of Hyperventilation in Routine Pediatric Electroencephalography - EEG Studies?
|ClinicalTrials.gov Identifier: NCT02766595|
Recruitment Status : Unknown
Verified March 2016 by Meir Medical Center.
Recruitment status was: Not yet recruiting
First Posted : May 10, 2016
Last Update Posted : May 10, 2016
|Condition or disease||Intervention/treatment||Phase|
|Epilepsy, Absence||Other: hyperventilation while sitting up during routine EEG||Not Applicable|
Hyperventilation is a very effective means of eliciting absence seizures in children with absence epilepsy. Worldwide EEG protocols for routine EEG recording include 3 minutes of hyperventilation. The whole EEG recording, including hyperventilation, is performed with the child lying down on a bed/coach. Our clinical experience suggests that the body position may affect the yield of hyperventilation in provoking the absence event. That is, hyperventilation may be more effective when the child is sitting up, Therefore, children referred for a routine EEG for suspected absence seizures will add 3 minutes of hyperventilation on a sitting position to the routine 3 minutes of supine hyperventilation. At least 5 minutes of rest will be allotted between both procedures.
Patients' caregivers will sign an informed consent form. Patients will randomly be divided into 2 groups: one group will first perform supine hyperventilation followed by sitting hyperventilation; the second group will perform hyperventilation in the opposite order, ie, first sitting up and then in supine position.
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||50 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Hyperventilation During Routine EEG in Children: the Impact of Body Position - Sitting vs Supine- on the Yield of the Procedure in Provoking Absence Seizures|
|Study Start Date :||June 2016|
|Estimated Primary Completion Date :||January 2017|
|Estimated Study Completion Date :||June 2017|
Non-drug: performing hyperventilation while sitting up during routine EEG
Other: hyperventilation while sitting up during routine EEG
Child will be asked to perform hyperventilation while lying down as well as while sitting up
- Differences in elapsed time (in seconds) to onset of absence seizure between lying supine and sitting up during hyperventilation in routine EEG. [ Time Frame: 6 months ]patients to be divided into 3 groups: Response A: occurrence of absence within 0-60 seconds; response B: within 60 - 120 seconds; response C: no occurrence of absence.
- Influence of order of performing hyperventilation, first supine and then sitting up, or vice-versa, on the time (in seconds) to occurrence of ansence seizures [ Time Frame: 6 months ]Response A: 0 - 60 secs; response B: 60 - 120 seconds; response C: no occurrence of absence