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Are Doctors Familiar With the Test Characteristics of Lung Cancer Screening?

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ClinicalTrials.gov Identifier: NCT02542332
Recruitment Status : Completed
First Posted : September 7, 2015
Last Update Posted : September 7, 2015
Sponsor:
Information provided by (Responsible Party):
Georg-Christian Funk, Otto Wagner Hospital

Brief Summary:
This study evaluates whether doctors are familiar with the statistical background of lung cancer screening.

Condition or disease Intervention/treatment Phase
Information About the Knowledge on the Statistical Background of Lung Cancer Screening of Doctors Other: With Data Not Applicable

Detailed Description:

Background: Screening with low-dose CT scan can prevent three deaths due to lung cancer among 1000 high-risk individuals. However, false-positive results and radiation exposure are relevant disadvantages deserving accurate consideration. Candidates for screening can only make an autonomous decision if doctors inform them correctly about the pros and cons of the method. Therefore, this study aims to evaluate, whether doctors understand the test characteristics of lung cancer screening.

Methods: In a randomized trial, 556 doctors (members of the Austrian Respiratory Society) will be invited to answer questions regarding lung cancer screening based on online case vignettes. Half of the participants will be randomized to the group 'with data' and will receive the correct solutions in advance. The group 'without data' will have to rely on prior knowledge or estimate. Primary endpoint will be the between-groups difference in the estimated number of deaths preventable by screening. Secondary endpoints will be the between-groups differences in prevalence of lung cancer, prevalence of suspicious results, sensitivity, specificity, positive-predictive value, and false negative rate. Estimations will also be compared to actual values from the literature.

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 556 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Health Services Research
Official Title: Are Doctors Familiar With the Test Characteristics of Lung Cancer Screening?
Study Start Date : May 2015
Actual Primary Completion Date : August 2015
Actual Study Completion Date : August 2015

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Lung Cancer

Arm Intervention/treatment
Active Comparator: With Data
Participants received statistical data about lung cancer screening
Other: With Data
The participants received statistical data about lung cancer screening in order to help them answer the questionaire

No Intervention: Without Data
Participants had no statistical data on lung cancer screening



Primary Outcome Measures :
  1. Between-groups difference in the estimated reduction of mortality due to lung cancer screening [ Time Frame: 14 days ]
    Participants had 14 days to complete the survey


Secondary Outcome Measures :
  1. Between-groups difference prevalence of lung cancer [ Time Frame: 14 days ]
    Participants had 14 days to complete the survey

  2. Between-groups difference in sensitivity of lung cancer screening [ Time Frame: 14 days ]
    Participants had 14 days to complete the survey

  3. Between-groups difference in the frequency of a positive test result [ Time Frame: 14 days ]
    Participants had 14 days to complete the survey

  4. Between-groups difference in specificity of lung cancer screening [ Time Frame: 14 days ]
    Participants had 14 days to complete the survey

  5. Between-groups difference in positive predictive value of lung cancer screening [ Time Frame: 14 days ]
    Participants had 14 days to complete the survey

  6. Between-groups difference in the false negative rate of lung cancer screening [ Time Frame: 14 days ]
    Participants had 14 days to complete the survey



Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Doctors, who were in training or had a completed specialization training in:
  • Pneumonology
  • Internal Medicine
  • Surgery
  • or Radiology

Exclusion Criteria:

  • Doctors, with a specialized training in
  • ENT
  • Pediatrics
  • Pathology and doctors who had no e-mail address were excluded.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02542332


Sponsors and Collaborators
Otto Wagner Hospital
Investigators
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Principal Investigator: Georg-Christian Funk, Assoc.Prof. Otto Wagner Hospital
Publications of Results:
Other Publications:

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
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Responsible Party: Georg-Christian Funk, Priv. Doz. Dr., Otto Wagner Hospital
ClinicalTrials.gov Identifier: NCT02542332    
Other Study ID Numbers: Lung Cancer screening
First Posted: September 7, 2015    Key Record Dates
Last Update Posted: September 7, 2015
Last Verified: August 2015
Keywords provided by Georg-Christian Funk, Otto Wagner Hospital:
lung cancer screening
statistical background
Additional relevant MeSH terms:
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Lung Neoplasms
Respiratory Tract Neoplasms
Thoracic Neoplasms
Neoplasms by Site
Neoplasms
Lung Diseases
Respiratory Tract Diseases