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Stimulus-response and Parkinson's Disease (SRlearning) (SRlearning)

This study is currently recruiting participants.
See Contacts and Locations
Verified February 2017 by Fondation Ophtalmologique Adolphe de Rothschild
Information provided by (Responsible Party):
Fondation Ophtalmologique Adolphe de Rothschild Identifier:
First received: July 30, 2015
Last updated: February 13, 2017
Last verified: February 2017

In a computerized experiment, visual stimuli will be presented to the parkinson's disease patients and to the controls. They will respond to each image by acting on the keyboard in a specific manner. Each participant will repeat that task 384 times per session. A break will be inserted every 12 tests so that participants can rest.

The experiment consists of three sessions. Each image will be presented three times. For the first two presentations it is assumed that a link will be created between the image and the task, and the image and action. In the third presentation, the same task and the same action will be maintained or will be swapped. In this way, It can be checked whether associations thus generated will affect the performance of the participants when tasks and actions will be incongruent.

Condition Intervention
Parkinson's Disease Behavioral: Stimulus-response

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: No masking
Primary Purpose: Basic Science
Official Title: Stimulus-response Associations in Parkinson's Disease Patients

Resource links provided by NLM:

Further study details as provided by Fondation Ophtalmologique Adolphe de Rothschild:

Primary Outcome Measures:
  • Reaction time (second) [ Time Frame: immediate ]

Estimated Enrollment: 100
Study Start Date: July 2015
Estimated Primary Completion Date: January 2018 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Parkinson's disease
Parkinson's disease patients
Behavioral: Stimulus-response
See summary
Healthy volunteers paired with Parkinson's disease patients on sex and age group, whose data will be extracted from a CNRS existing database
Behavioral: Stimulus-response
See summary


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Patient : Parkinson's disease Controls: healthy volunteers paired to patients on sex and age group

Exclusion Criteria:

  • Other neurological condition
  • Known pregnancy or breastfeeding woman
  • No medical insurance coverage
  • Person under legal protection
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT02515136

Contact: Laurence Salomon, MD,PhD +33148036431

Fondation Ophtalmologique A. de Rothschild Recruiting
Paris, France, 75019
Contact: Laurence Salomon    +33148036431   
Contact: Lucia Lopes    +33148036434   
Principal Investigator: Jean-Philippe Brandel, MD         
Sponsors and Collaborators
Fondation Ophtalmologique Adolphe de Rothschild
  More Information

Responsible Party: Fondation Ophtalmologique Adolphe de Rothschild Identifier: NCT02515136     History of Changes
Other Study ID Numbers: JBL_2014-29
Study First Received: July 30, 2015
Last Updated: February 13, 2017

Additional relevant MeSH terms:
Parkinson Disease
Parkinsonian Disorders
Basal Ganglia Diseases
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Movement Disorders
Neurodegenerative Diseases processed this record on July 19, 2017