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Stimulus-response and Parkinson's Disease (SRlearning) (SRlearning)

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ClinicalTrials.gov Identifier: NCT02515136
Recruitment Status : Completed
First Posted : August 4, 2015
Last Update Posted : February 9, 2018
Sponsor:
Information provided by (Responsible Party):
Fondation Ophtalmologique Adolphe de Rothschild

Brief Summary:

In a computerized experiment, visual stimuli will be presented to the parkinson's disease patients and to the controls. They will respond to each image by acting on the keyboard in a specific manner. Each participant will repeat that task 384 times per session. A break will be inserted every 12 tests so that participants can rest.

The experiment consists of three sessions. Each image will be presented three times. For the first two presentations it is assumed that a link will be created between the image and the task, and the image and action. In the third presentation, the same task and the same action will be maintained or will be swapped. In this way, It can be checked whether associations thus generated will affect the performance of the participants when tasks and actions will be incongruent.


Condition or disease Intervention/treatment Phase
Parkinson's Disease Behavioral: Stimulus-response Not Applicable

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 100 participants
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Basic Science
Official Title: Stimulus-response Associations in Parkinson's Disease Patients
Actual Study Start Date : July 1, 2015
Actual Primary Completion Date : January 2018
Actual Study Completion Date : January 2018

Resource links provided by the National Library of Medicine


Arm Intervention/treatment
Experimental: Parkinson's disease
Parkinson's disease patients
Behavioral: Stimulus-response
See summary

Controls
Healthy volunteers paired with Parkinson's disease patients on sex and age group, whose data will be extracted from a CNRS existing database
Behavioral: Stimulus-response
See summary




Primary Outcome Measures :
  1. Reaction time (second) [ Time Frame: immediate ]


Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Patient : Parkinson's disease Controls: healthy volunteers paired to patients on sex and age group

Exclusion Criteria:

  • Other neurological condition
  • Known pregnancy or breastfeeding woman
  • No medical insurance coverage
  • Person under legal protection

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02515136


Locations
France
Fondation Ophtalmologique A. de Rothschild
Paris, France, 75019
Sponsors and Collaborators
Fondation Ophtalmologique Adolphe de Rothschild

Responsible Party: Fondation Ophtalmologique Adolphe de Rothschild
ClinicalTrials.gov Identifier: NCT02515136     History of Changes
Other Study ID Numbers: JBL_2014-29
First Posted: August 4, 2015    Key Record Dates
Last Update Posted: February 9, 2018
Last Verified: February 2018

Additional relevant MeSH terms:
Parkinson Disease
Parkinsonian Disorders
Basal Ganglia Diseases
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Movement Disorders
Neurodegenerative Diseases