Protein Requirements in Endurance-trained Athlete (EP)
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|ClinicalTrials.gov Identifier: NCT02478801|
Recruitment Status : Completed
First Posted : June 23, 2015
Last Update Posted : June 16, 2016
Protein requirements in individuals who participate in endurance-based exercise training have been suggested to be greater than the current recommended dietary allowance (RDA).
Nutritional requirements for dietary amino acids in adults have traditionally been determined utilizing the nitrogen balance technique, which is prone to underestimating protein requirements. As a result, there is a need to re-evaluate recommendations in order to characterize how dietary amino acid needs may be modulated by physical activity.
Recent studies using the minimally invasive indicator amino acid oxidation (IAAO) technique have suggested that protein requirements in young men are at least 50% higher than RDA based on nitrogen balance data.
Therefore, the purpose of this study is to measure the protein requirement in endurance trained adults using the IAAO technique.
|Condition or disease||Intervention/treatment||Phase|
|Increased Metabolic Requirement Healthy||Dietary Supplement: amino acids intake||Early Phase 1|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||9 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Primary Purpose:||Basic Science|
|Official Title:||Evaluation of Protein Requirements in Male Endurance Athletes|
|Study Start Date :||March 2015|
|Actual Primary Completion Date :||January 2016|
|Actual Study Completion Date :||May 2016|
Experimental: Endurance trained
subjects will receive different levels of amino acids intakes varying from 0.2 to 2.8 g/kg/day.
Dietary Supplement: amino acids intake
amino acids intakes will be varied at 0.2-2.8 g/kg/day
- 13CO2 (carbon dioxide) excretion (μmol/kg/h) [ Time Frame: 4 hours / study day ]
- [13C]phenylalanine oxidation (μmol/kg/h) [ Time Frame: 4 hours/study day ]