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Investigating the Role of Mucin and Mucin Glycosylating Enzymes in Nasopharyngeal Carcinoma and Salivary Gland Cancer and Their Correlation With Clinical Prognosis

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ClinicalTrials.gov Identifier: NCT02401763
Recruitment Status : Unknown
Verified March 2015 by National Taiwan University Hospital.
Recruitment status was:  Not yet recruiting
First Posted : March 30, 2015
Last Update Posted : April 3, 2015
Sponsor:
Information provided by (Responsible Party):
National Taiwan University Hospital

Brief Summary:
Nasopharyngeal carcinoma (NPC) is the tenth leading cancers in Taiwan and investigating its biomarker is important for understanding the mechanism of its pathogenesis.

Condition or disease
Salivary Gland Cancer Nasopharyngeal Carcinoma

Detailed Description:
NPC is the tenth leading cancers in Taiwan and investigating its biomarker is important for understanding the mechanism of its pathogenesis.

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Study Type : Observational
Estimated Enrollment : 200 participants
Time Perspective: Retrospective
Official Title: Investigating the Role of Mucin and Mucin Glycosylating Enzymes in Nasopharyngeal Carcinoma and Salivary Gland Cancer and Their Correlation With Clinical Prognosis
Study Start Date : April 2015
Estimated Primary Completion Date : April 2016

Resource links provided by the National Library of Medicine


Group/Cohort
Nasopharyngeal carcinoma and salivary gland tumor
patients diagnosed and treated in National Taiwan University Hospital



Primary Outcome Measures :
  1. The difference of expression level of mucin glycosylating enzymes (by immunohistochemistry) in nasopharyngeal carcinoma and salivary gland tissues [ Time Frame: 1~5 years after patients received definite therapy ]


Information from the National Library of Medicine

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Ages Eligible for Study:   20 Years to 80 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
NPC and salivary gland tumor diagnosed and treated in HTUH
Criteria

Inclusion Criteria:

  • NPC and salivary gland tumor diagnosed and treated in HTUH

Exclusion Criteria:

  • previous treatment or surgery

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02401763


Contacts
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Contact: Mei-Chun Lin, MD 886-972-654-470 mayandjean@gmail.com
Contact: Pei-Jen Lou, MD, PhD pjlou@ntu.edu.tw

Sponsors and Collaborators
National Taiwan University Hospital
Investigators
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Principal Investigator: Pei-Jen Lou NTUH

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Responsible Party: National Taiwan University Hospital
ClinicalTrials.gov Identifier: NCT02401763     History of Changes
Other Study ID Numbers: 201412126RIND
First Posted: March 30, 2015    Key Record Dates
Last Update Posted: April 3, 2015
Last Verified: March 2015
Keywords provided by National Taiwan University Hospital:
biomarker
Additional relevant MeSH terms:
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Carcinoma
Nasopharyngeal Carcinoma
Salivary Gland Neoplasms
Neoplasms, Glandular and Epithelial
Neoplasms by Histologic Type
Neoplasms
Nasopharyngeal Neoplasms
Pharyngeal Neoplasms
Otorhinolaryngologic Neoplasms
Head and Neck Neoplasms
Neoplasms by Site
Nasopharyngeal Diseases
Pharyngeal Diseases
Stomatognathic Diseases
Otorhinolaryngologic Diseases
Mouth Neoplasms
Mouth Diseases
Salivary Gland Diseases