Optic Nerve Sheath Diameter in Patients With Intracranial Pathology
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|ClinicalTrials.gov Identifier: NCT02361671|
Recruitment Status : Recruiting
First Posted : February 12, 2015
Last Update Posted : April 17, 2018
Elevated intracranial pressure (ICP) is a common and potentially life threatening condition arising from a variety of pathological conditions. The ability to monitor ICP is a crucial aspect in the management of these patients. Currently, the diagnosis of whether ICP is elevated or not is determined either with clinical signs (headache, nausea and vomiting or visual disturbances) or from the changes in the preoperative neuroimaging modalities such as computerized tomography (CT scan) and/or magnetic resonance imaging (MRI).
Recently, transorbital ultrasonography has gained popularity as a noninvasive bedside exam that has been shown to be useful in the diagnosis of raised ICP by evaluating the change in the optic nerve sheath diameter (ONSD).
The aim of our study is to use transorbital ultrasound to evaluate ONSD changes in patients with intracranial pathology and to compare the changes in the ONSD before and after surgical intervention as well as between patients with and without clinical or radiological signs of increased ICP.
|Condition or disease||Intervention/treatment|
|Elevated Intracranial Pressure (ICP)||Other: Optic Nerve Sheath Diameter using an ultrasound|
|Study Type :||Observational|
|Estimated Enrollment :||100 participants|
|Official Title:||Ultrasonographic Assessment of the Optic Nerve Sheath Diameter in Patients With Intracranial Pathology|
|Study Start Date :||February 2015|
|Estimated Primary Completion Date :||October 2018|
|Estimated Study Completion Date :||December 2018|
- Other: Optic Nerve Sheath Diameter using an ultrasound
Optic nerve sheath diameter will be measured by ultrasound preoperatively on the day of surgery, Immediate postoperative period (within 24 hours) or 6-8 weeks after surgery on the follow-up visit.
- Optic Nerve Sheath Diameter, as measured by ultrasound of the optic nerve" [ Time Frame: upto 6-8 weeks ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02361671
|Toronto Western Hospital||Recruiting|
|Toronto, Ontario, Canada, M5T2S8|
|Contact: Lashmi Venkatraghavan, MD 4166035118 email@example.com|
|Principal Investigator: Dr Lashmi Venkatraghavan, MD|
|Sub-Investigator: Dr Vincent Chan, MD|
|Sub-Investigator: Dr. Michael Dinsmore, MD|
|Sub-Investigator: Dr. Jigesh Mehta, MD|