Lean Body Mass Response to Higher-protein Diets During Winter Military Training
|Body Weight||Dietary Supplement: Control Dietary Supplement: Protein Dietary Supplement: Carbohydrate|
|Study Design:||Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple (Participant, Investigator, Outcomes Assessor)
Primary Purpose: Basic Science
|Official Title:||Effects of Carbohydrate and Protein Supplementation on Whole-body Protein Balance and Skeletal Muscle Mass During Winter Military Training: a Randomized Controlled Trial|
- Protein Balance [ Time Frame: day 5 ]Whole-body nitrogen balance
- Lean Body Mass [ Time Frame: day 5 ]Body composition
- Skeletal Muscle Mass [ Time Frame: day 5 ]Isotopic estimates of muscle protein mass
- Body weight [ Time Frame: day 5 ]
- Intestinal health [ Time Frame: day 5 ]Gut health
- Thermal and Physiological Strain [ Time Frame: average 6 days ]Core and skin temperature, heart rate, respiration rate
|Study Start Date:||January 2015|
|Study Completion Date:||February 2015|
|Primary Completion Date:||February 2015 (Final data collection date for primary outcome measure)|
Placebo Comparator: Control
3 Combat rations only per day. No additional experimental food items (those assigned to the active comparator groups will consume isoenergetic carbohydrate and protein-based food products).
Dietary Supplement: Control
Other Name: Placebo (Rations Only)
Active Comparator: Protein
Consume 4 whey protein-based snack-bars in addition to 3 combat rations each day during training.
Dietary Supplement: Protein
Other Name: Protein Bar
Active Comparator: Carbohydrate
Consume 4 carbohydrate-based snack-bars in addition to 3 combat rations each day during training.
Dietary Supplement: Carbohydrate
Other Name: Granola Bar
Up to 120 Norwegian Soldiers from the 2nd Battalion, Brigade North, Norwegian Army stationed at Skjold Garrison will be enrolled in a 9-day, randomized controlled study. Using dietary analysis, body composition assessments, stable isotope methodologies, basic biochemical techniques, and measures of physiological strain, the effects of supplemental energy in the form of carbohydrate and protein on indices of muscle mass and physiological status will be assessed.
We hypothesize that consuming supplemental energy will attenuate the effects of severe energy deficit on inflammation, androgenic hormones, and whole-body protein retention, thereby protecting skeletal muscle mass. We expect that consuming PRO will promote a more favorable recovery than consuming CHO, as indicated by measures of increased whole-body protein synthesis and greater conservation of skeletal muscle mass.
Please refer to this study by its ClinicalTrials.gov identifier: NCT02327208
|United States, Massachusetts|
|US Army Research Institute of Environmental Medicine|
|Natick, Massachusetts, United States, 01760|
|Norwegian Defense Research Establishment|