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Home Bicycle Exercise and Aerobic Capacity

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ClinicalTrials.gov Identifier: NCT02268292
Recruitment Status : Completed
First Posted : October 20, 2014
Last Update Posted : October 20, 2014
Sponsor:
Information provided by (Responsible Party):
TCVGH, Taichung Veterans General Hospital

Brief Summary:
The subjects with MetS or type 2 diabetes were enrolled for this exercise-training program. All participators underwent an indoor bicycle exercise for twelve weeks. In addition to demographic data and biochemical tests were determined after an overnight fasting. Extension of muscle strength was detected in the dominant lower extremity.

Condition or disease Intervention/treatment Phase
Metabolic Cardiovascular Syndrome Behavioral: bicycle exercise Phase 4

Detailed Description:
This prospective open-labeled study was conducted in Taichung Veterans General Hospital. The adult participants with metabolic syndrome and/or type 2 diabetes were enrolled. MetS. The procedures were fully explained to all subjects before the cardiopulmonary exercise test. ll enrolled subjects received a scheduled twelve-week program for exercise-training program. A commercially available bicycle with an indoor bicycle trainer are used as the home exercise training modality. All medications were not allowed to be changed during the study.

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 37 participants
Allocation: N/A
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: The Effects of Home Bicycle Exercise Program on Hyperlipidemia, Hypertension, Blood Sugar Control, Muscle Strength and Aerobic Capacity
Study Start Date : August 2012
Actual Primary Completion Date : August 2014
Actual Study Completion Date : August 2014

Resource links provided by the National Library of Medicine


Arm Intervention/treatment
Experimental: Bicycle Exercise
Bicycle Exercise for 12 weeks
Behavioral: bicycle exercise
All enrolled subjects received a scheduled twelve-week exercise program. A commercially available bicycle (Giant CS800, Taichung, Taiwan) with an indoor bicycle stand (Giant Cyclotron Mag, Taichung, Taiwan) was used as the home exercise training modality.




Primary Outcome Measures :
  1. Metabolic syndrome [ Time Frame: 12 weeks ]
    Components of metabolic syndrome based on the modified Third Report of the National Cholesterol Education Program (NCEP) criteria


Secondary Outcome Measures :
  1. Muscle strength [ Time Frame: 12 weeks ]
    A Biodex Isokinetic Dynamometer (Biodex Medical Systems, Inc., Shirley, New York, USA) was used to evaluate the muscle strength of the subjects

  2. Brain-derived neurotrophic factor [ Time Frame: 12 weeks ]
    Serum concentration of Brain-derived neurotrophic factor (enzyme immunoassay method, R&D Systems, Minneapolis, U.S.A.)

  3. Arterial stiffness [ Time Frame: 12 weeks ]
    Pulse wave velocity



Information from the National Library of Medicine

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Ages Eligible for Study:   20 Years to 85 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Adult with metabolic syndrome or type 2 diabetes

Exclusion Criteria:

  • hyperglycemic crisis or HbA1c > 12%;
  • serum creatinine levels greater than 200 mmol/L;
  • acute or chronic infectious diseases;
  • limitations in the ability to undertake regular exercise
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
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Responsible Party: TCVGH, Taichung Veterans General Hospital
ClinicalTrials.gov Identifier: NCT02268292    
Other Study ID Numbers: SG12147
First Posted: October 20, 2014    Key Record Dates
Last Update Posted: October 20, 2014
Last Verified: October 2014
Keywords provided by TCVGH, Taichung Veterans General Hospital:
Metabolic syndrome
Diabetes
Muscle strength
Aerobic exercise
Bicycle
Brain-derived neurotrophic factor
Additional relevant MeSH terms:
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Metabolic Syndrome
Insulin Resistance
Hyperinsulinism
Glucose Metabolism Disorders
Metabolic Diseases