Parathyroid Reimplantation in Forearm Subcutaneous Tissue During Thyroidectomy: a Simple Way to Avoid Ipoparathyroidism and Evaluate Graft Function
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ClinicalTrials.gov Identifier: NCT02194920
: July 18, 2014
Last Update Posted
: November 5, 2014
University of Roma La Sapienza
Information provided by (Responsible Party):
Giuseppe Cavallaro, University of Roma La Sapienza
The purpose of this study is to evaluate safety and effectiveness of normal parathyroid tissue reimplantation in forearm subcutaneous tissue in case of accidental removal of parathyroid gland during thyroid surgery.
Assessment of parathyroid tissue graft function by selective (left or right) parathormone measurement by vein blood sample [ Time Frame: up to 3 months ]
The primary outcome will be the assessment of reimplanted parathyroid function, evaluated by intact Parathormone (iPTH) measurement by separate blood samples (left and right arm) at 7 days, 1 month and 3 months after surgery. Ratio of 1.5 between the iPTH levels in the arm receiving graft and the opposite arm will be predictive of graft functionality
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Ages Eligible for Study:
Child, Adult, Senior
Sexes Eligible for Study:
Accepts Healthy Volunteers:
All patients receiving thyroid surgery with accidental removal or devascularization of normal parathyroid gland
Patients affected by benign thyroid disease undergoing thyroidectomy