The Effect of Blood Transfusion on Endothelial Function
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|ClinicalTrials.gov Identifier: NCT02161042|
Recruitment Status : Completed
First Posted : June 11, 2014
Last Update Posted : October 5, 2016
Blood transfusion is often used to treat patients with Anemia. The period of storage of blood products prior to use for transfusion may vary. Prolonged storage of blood products may result in changing their biochemistry.
This study aims to look into whether the transfusion of "old" blood, which is stored for more than 7 days, as compared to the transfusion of "Fresh" blood, which is stored for less than 7 days, will affect endothelial function.
|Condition or disease|
|Study Type :||Observational|
|Estimated Enrollment :||40 participants|
|Official Title:||The Effect of Blood Transfusion on Endothelial Function|
|Study Start Date :||August 2011|
|Actual Primary Completion Date :||January 2016|
|Actual Study Completion Date :||June 2016|
|fresh blood Transfusion|
|Old blood transfusion|
- Endothelial function [ Time Frame: Change in endothelial function compared to baseline. Test is done 15 minutes prior to transfusion and 30 minutes post blood transfusion. The test is repeated when patient received another blood transfusion. The results of the change are compared. ]The function of the blood vessels will be assessed with the EndoPAT device. This test is done 15 minutes prior to the transfusion and again 30 minutes post the transfusion. Patients that will receive both fresh and old blood will be included.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02161042
|London Health Sciences Centre|
|London, Ontario, Canada, N6A5A5|