Fasting Predictors of OGTT and MMTT Response

This study is ongoing, but not recruiting participants.
Information provided by (Responsible Party):
Health Diagnostic Laboratory, Inc. Identifier:
First received: November 25, 2013
Last updated: February 12, 2015
Last verified: February 2015
  1. To develop a database containing matched information from dynamic tests of postprandial glycemic control (OGTT or MMTT), results of a broad panel of fasting biomarkers, and clinical information related to diabetes risk obtain through subject interview.
  2. To use the database to identify fasting biomarkers and associated algorithms to best predict parameters derived from dynamic tests (OGTT or MMTT) such as Insulin Glucose Tolerance (IGT), impaired first phase insulin response, etc., controlling for clinical information such as current medication use.

Cardiovascular Disease

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Identification of Fasting Biomarkers That Predict Responses to the Oral Glucose Tolerance Test (OGTT) and Mixed Meal Tolerance Test (MMTT)

Further study details as provided by Health Diagnostic Laboratory, Inc.:

Primary Outcome Measures:
  • Identify fasting biomarkers and associated algorithms to predict parameters [ Time Frame: Baseline ] [ Designated as safety issue: No ]
    To assess relations between baseline factors and patterns of change over time due to feeding treatments.

Biospecimen Retention:   Samples With DNA
Whole blood and serum

Estimated Enrollment: 1000
Study Start Date: August 2013
Estimated Study Completion Date: August 2018
Estimated Primary Completion Date: August 2018 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Representative of the ethnic population of Richmond, VA

Inclusion Criteria:

  • Weight >95

Exclusion Criteria:

  • Prior diagnosis of Diabetes
  Contacts and Locations
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Please refer to this study by its identifier: NCT01998867

United States, Virginia
Health Diagnostic Laboratory, Inc.
Richmond, Virginia, United States, 23224
Sponsors and Collaborators
Health Diagnostic Laboratory, Inc.
Principal Investigator: Szilard Voros, MD Health Diagnostic Laboratory, Inc.
  More Information


Responsible Party: Health Diagnostic Laboratory, Inc. Identifier: NCT01998867     History of Changes
Other Study ID Numbers: R2013-1003
Study First Received: November 25, 2013
Last Updated: February 12, 2015
Health Authority: United States: Institutional Review Board

Additional relevant MeSH terms:
Cardiovascular Diseases processed this record on November 25, 2015