Mucin Glycosylating Enzymes in Head and Neck Cancers
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT01976377|
Recruitment Status : Unknown
Verified December 2016 by National Taiwan University Hospital.
Recruitment status was: Recruiting
First Posted : November 5, 2013
Last Update Posted : December 15, 2016
|Condition or disease|
|Glycosyltion Enzymes and Function Abnormalities|
Glycosylation is the most common post-translational modification of proteins. Aberrant glycosylation is the hallmark of most human cancers and affect many cellular properties, including cell proliferation, apoptosis, differentiation, transformation, migration and immune response.
Though widely explored in various human cancers, the role of mucin glycosylating enzymes in HNSCC has not been elucidated. Our aims is to analyze the expression patterns of mucin glycosylating enzymes in HNSCC tissues. Furthermore, we will correlate the expression levels of mucin glycosylating enzymes with clinical characteristics of HNSCC patients.
|Study Type :||Observational|
|Estimated Enrollment :||200 participants|
|Observational Model:||Case Control|
|Official Title:||Expression of Mucin Glycosylating Enzymes in Head and Neck Cancers and Its Correlation With Clinico-pathological Parameters.|
|Study Start Date :||October 2013|
|Estimated Primary Completion Date :||October 2017|
|Estimated Study Completion Date :||October 2017|
Stage I, II, III, IV HNSCC
Stage I, II, III, IV HNSCC reveive treatment in NTUH
- Measure the expression of mucin glycosylating in head and neck cancer [ Time Frame: 1~5 years after patient received surgery ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01976377
|Contact: Pei-Jen Lou, M.D, Ph.Dfirstname.lastname@example.org|
|Contact: Mei-Chun Linemail@example.com|
|National Taiwan University||Recruiting|
|Taipei, Taiwan, 100|
|Contact: Pei-Jen Lou, MD, PhD 886-972651527 firstname.lastname@example.org|
|Contact: Mei-Chun Lin 886-978261268 email@example.com|
|Principal Investigator: Pei-Jen Lou, M.D, Ph.D|
|Principal Investigator:||Pei-Jen Lou, M.D, Ph.D||National Taiwan University Hospital|