Viral Illness in Pediatric Critical Care: Incidence Timing & Severity of Associated Heart Dysfunction & Acute Kidney Injury (MyDAKI-01)
The purpose of this study is to be able to better describe the incidence, timing and severity of myocardial dysfunction and acute kidney injury (AKI) following a documented respiratory viral illness (RSV, adenovirus, metapneumovirus, parainfluenza, influenza, etc.) in pediatric patients.
Acute Kidney Injury
|Study Design:||Observational Model: Case-Only|
|Official Title:||Viral Illness in the Pediatric Critical Care Setting: the Incidence, Timing and Severity of Associated Myocardial Dysfunction and Acute Kidney Injury.|
- Myocardial dysfunction, as defined by a low ejection fraction on an Echocardiogram. [ Time Frame: up to 7 days ] [ Designated as safety issue: Yes ]
- Acute Kidney Injury (AKI) as defined by the meeting of the pediatric RIFLE criteria. [ Time Frame: up to 7 days ] [ Designated as safety issue: Yes ]
|Study Start Date:||September 2013|
|Estimated Study Completion Date:||July 2015|
|Estimated Primary Completion Date:||July 2015 (Final data collection date for primary outcome measure)|
This is a single-centre, prospective and retrospective, descriptive data-collection pilot study.
Prospective Data Collection:
All pediatric patients who are less than 18 years with a confirmed positive respiratory viral swab will be invited to participate.
Retrospective Data Collection:
The retrospective portion of this study will examine a 5 year period prior to the start of enrollment for the prospective study, with the intention to include all pediatric patients who are less than 18 years with a confirmed positive respiratory viral swab and admitted into the local hospital's PICU.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01924663
|Contact: Tanya Holt, M.D.||(306) email@example.com|
|Royal University Hospital||Recruiting|
|Saskatoon, Saskatchewan, Canada, S7N 0W8|
|Principal Investigator: Tanya Holt, MD FRCPC|
|Sub-Investigator: William Bingham, MD FRCPC|
|Sub-Investigator: Ashok Kakadekar, MD FRCPC|
|Principal Investigator:||Tanya Holt, M.D.||University of Saskatchewan|