We're building a better ClinicalTrials.gov. Check it out and tell us what you think!
Try the New Site
We're building a modernized ClinicalTrials.gov! Visit Beta.ClinicalTrials.gov to try the new functionality.
Working…
ClinicalTrials.gov
ClinicalTrials.gov Menu

Impact of Chronic Air Pollution on Non-cystic Fibrosis Bronchiectasis

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT01906047
Recruitment Status : Completed
First Posted : July 23, 2013
Last Update Posted : July 23, 2013
Sponsor:
Information provided by (Responsible Party):
Dr. Lieven Dupont, Universitaire Ziekenhuizen KU Leuven

Study Description
Go to 
Top of Page Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information
Brief Summary:
We aim at investigation the impact of chronic air pollution exposure on non-cystic fibrosis bronchiectasis outcome.

Condition or disease
Bronchiectasis

Detailed Description:
  • Patient files will be search for time of death and cause of death.
  • Other variables will be collected: bacterial culture results, therapy, gender, age, etc.
  • These data will be linked with pollution data: trafic load, distance to major road, etc.
Study Design
Go to 
Top of Page Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information

Layout table for study information
Study Type : Observational [Patient Registry]
Actual Enrollment : 189 participants
Observational Model: Cohort
Time Perspective: Prospective
Target Follow-Up Duration: 6 Years
Official Title: Impact of Chronic Air Pollution on Non-cystic Fibrosis Bronchiectasis
Study Start Date : June 2006
Actual Primary Completion Date : October 2012
Actual Study Completion Date : April 2013

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Air Pollution

Groups and Cohorts
Go to 
Top of Page Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information


Outcome Measures
Go to 
Top of Page Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information

Primary Outcome Measures :
  1. Death [ Time Frame: 6 years ]
    From June 2006 till October 2012, enrolled patients' medical file will be screened if death has occurred. If so, cause of death will be search for in the patients' file.


Eligibility Criteria
Go to 
Top of Page Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Layout table for eligibility information
Ages Eligible for Study:   18 Years to 65 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients with a HRCT diagnosis of bronchiectasis and do not have a diagnosis of cystic fibrosis. They also need to have typical bronchiectatic disease (recurrent infections and sputum).
Criteria

Inclusion Criteria:

  • HRCT diagnosis of bronchiectasis
  • recurrent infections or chronic sputum production
  • patients between 18 and 65 years old.

Exclusion Criteria:

  • Cystic Fibrosis
  • Tumoral disease
  • Traction bronchiectasis due to interstitial lung disease
  • patients older than 65 years or younger than 18 years at recruitment
  • COPD
Contacts and Locations
Go to 
Top of Page Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01906047


Locations
Layout table for location information
Belgium
UZ Leuven
Leuven, Vlaams-Brabant, Belgium, 3000
Sponsors and Collaborators
Universitaire Ziekenhuizen KU Leuven
Investigators
Layout table for investigator information
Principal Investigator: Lieven J Dupont, MD, PhD UZ Leuven
Principal Investigator: Pieter C Goeminne, MD UZ Leuven
More Information
Go to 
Top of Page Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information
Additional Information:

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):

Layout table for additonal information
Responsible Party: Dr. Lieven Dupont, Prof. Dr. Lieven Dupont, Universitaire Ziekenhuizen KU Leuven
ClinicalTrials.gov Identifier: NCT01906047    
Other Study ID Numbers: NCFB chronic pollution
First Posted: July 23, 2013    Key Record Dates
Last Update Posted: July 23, 2013
Last Verified: July 2013
Keywords provided by Dr. Lieven Dupont, Universitaire Ziekenhuizen KU Leuven:
Non-cystic fibrosis bronchiectasis
Additional relevant MeSH terms:
Layout table for MeSH terms
Bronchiectasis
Fibrosis
Pathologic Processes
Bronchial Diseases
Respiratory Tract Diseases