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Brain Functions in Patients Before and After Bariatric Surgery

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ClinicalTrials.gov Identifier: NCT01900483
Recruitment Status : Completed
First Posted : July 16, 2013
Last Update Posted : November 10, 2015
Sponsor:
Information provided by (Responsible Party):
Sabine Frank, University Hospital Tuebingen

Brief Summary:
The project will specifically focus on the examination of the influence of substantial weight loss due to bariatric surgery on brain functions. Our hypothesis is that substantial weight loss after Bariatric Surgery (BS) is also accompanied by changes in the balance of reward and inhibitory networks in diabetic subjects. Therefore the investigators will conduct a functional magnetic resonance imaging (fMRI) study investigating functional measures.

Condition or disease
Adiposity

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Study Type : Observational
Actual Enrollment : 24 participants
Observational Model: Case Control
Time Perspective: Cross-Sectional
Actual Primary Completion Date : August 2014

Resource links provided by the National Library of Medicine


Group/Cohort
pre bariatric surgery
post bariatric surgery



Primary Outcome Measures :
  1. Differential brain functions [ Time Frame: at least 6 months after bariatric surgery (experimental group) ]
    brain functions will be measured by blood oxygen level dependent effects


Other Outcome Measures:
  1. Behavioral measurements [ Time Frame: pre surgery (group 1) and at least 6 months after surgery ]
    eating behavior



Information from the National Library of Medicine

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Ages Eligible for Study:   25 Years to 65 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Sampling Method:   Non-Probability Sample
Study Population
volunteers pre and post bariatric surgery
Criteria

Inclusion Criteria:

  • bariatric surgery in the past or in the future
  • diabetes (at least before surgery)

Exclusion Criteria:

  • fMRI contraindications
  • claustrophobia

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01900483


Locations
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Germany
University Clinic of Tuebingen, MEG Center
Tuebingen, Germany, 72076
Sponsors and Collaborators
University Hospital Tuebingen

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
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Responsible Party: Sabine Frank, Dr., University Hospital Tuebingen
ClinicalTrials.gov Identifier: NCT01900483     History of Changes
Other Study ID Numbers: BSD
First Posted: July 16, 2013    Key Record Dates
Last Update Posted: November 10, 2015
Last Verified: November 2015
Additional relevant MeSH terms:
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Obesity
Overnutrition
Nutrition Disorders
Overweight
Body Weight
Signs and Symptoms