Try our beta test site
IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more...

Role of Subsequent Atrial Tachycardia in Mechanisms of Persistent AF

This study has been completed.
Information provided by (Responsible Party):
Thomas Rostock, Johannes Gutenberg University Mainz Identifier:
First received: July 6, 2013
Last updated: July 10, 2013
Last verified: July 2013
In this study, the investigators aim to examine the prognostic role of subsequent Atrial Tachycardias (ATs) in the mechanisms of atrial fibrillation (AF). Therefore, the investigators compare patients who were randomly assigned to either undergo cardioversion after AF has been terminated to AT or further ablation until the achievement of sinus rhythm.

Condition Intervention
Atrial Fibrillation
Procedure: Catheter ablation of subsequent atrial tachycardia

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: The Prognostic Role of Subsequent Atrial Tachycardias Occurring After Atrial Fibrillation Termination: A Prospective Randomized Trial

Resource links provided by NLM:

Further study details as provided by Johannes Gutenberg University Mainz:

Primary Outcome Measures:
  • Arrhythmia-free survival [ Time Frame: 24 months after enrolment ]

Secondary Outcome Measures:
  • Type of Arrhythmia recurrence [ Time Frame: 24 months after enrolement ]

Other Outcome Measures:
  • Time to recurrence [ Time Frame: after blanking period (3 months) until study end (at least 24 months) ]

Enrollment: 110
Study Start Date: June 2009
Primary Completion Date: March 2013 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Group A: cardioversion at AT
after achievement of AT, pts were cardioverted
Group B: ablation to SR
After AT has been achieved, all subsequent AT were ablated with the endpoint of procedural SR termination
Procedure: Catheter ablation of subsequent atrial tachycardia


Ages Eligible for Study:   18 Years to 85 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients with persistent AF

Inclusion Criteria:

  • persistent AF for at least 1 months,
  • age > 18 years,
  • refractory to drug therapy,
  • no prior ablation

Exclusion Criteria:

  • prior AF ablation
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01896570

University Hospital Eppendorf, Dept. of Electrophysiology
Hamburg, Germany, D-20246
Sponsors and Collaborators
Johannes Gutenberg University Mainz
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Thomas Rostock, Univ.-Prof. Dr. med., Johannes Gutenberg University Mainz Identifier: NCT01896570     History of Changes
Other Study ID Numbers: Ciritical endpoint HH
Study First Received: July 6, 2013
Last Updated: July 10, 2013

Keywords provided by Johannes Gutenberg University Mainz:
atrial fibrillation
catheter ablation
subsequent atrial tachycardia

Additional relevant MeSH terms:
Atrial Fibrillation
Arrhythmias, Cardiac
Heart Diseases
Cardiovascular Diseases
Pathologic Processes processed this record on April 26, 2017