Maintenance Transcranial Electrical Stimulation for Depression
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Transcranial electrical stimulation (TES) techniques offer a novel treatment approach for depression and have shown promising efficacy. However, there is no published data to date on their effectiveness as a maintenance treatment. This study will investigate ways of using TES as a maintenance treatment to prevent relapse in depression.
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Ages Eligible for Study:
18 Years and older (Adult, Senior)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
All participants will be ≥ 18 years old.
Participants must have experienced a significant clinical response, defined as ≥ 50% decrease from baseline scores on the Montgomery Asberg Depression Rating Scale (MADRS).
Inadequate response to acute trial of TES.
Clinically defined neurological disorder or insult.
Metal in the cranium, skull defects, or skin lesions on scalp (cuts, abrasions, rash) at proposed electrode sites.
Pregnancy (women of childbearing age will be asked to undergo a urine pregnancy test prior to starting the study).
Concurrent long acting benzodiazepines, ritalin or dexamphetamine medication.
Treatment for depression is changed during months 3-9 of the trial.