Evaluation of Immune Signaling Networks in Healthy Human Volunteers
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The purpose of this study is to better understand whether and to what extent the activity of immune cells in blood varies over time under normal conditions as assessed in healthy subjects. Results of this study will provide the foundation for helping us evaluate changes in immune cell activities in response to surgery and drugs used in anesthesia. The overall purpose of our research is to understand immune health in the context of anesthesia and surgery.
Numerical and functional changes of circulating immune cells over time in healthy individuals [ Time Frame: Day 1, Day 2, Day 7, Day 28 ]
This is an exploratory study. Numerical and functional (phosphorylation of signaling molecules and transcription factors) behavior of all circulating immune cells will be captured. Blood specimens collected at referenced time points will be analyzed with mass cytometry.
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Layout table for eligibility information
Ages Eligible for Study:
18 Years to 50 Years (Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Study population consists of a community sample.
Good general health
Recent cold or flu
Chronic use of medications affecting the immune system