Eye Movements and Reading Disabilities (EOMRD)
|ClinicalTrials.gov Identifier: NCT01860027|
Recruitment Status : Terminated (Lack of enrollment)
First Posted : May 22, 2013
Last Update Posted : May 20, 2015
The mechanism of the eye movement anomalies seen in dyslexic patients is not well defined. Some optometrists use observational eye movement tests as screening devices for dyslexia and advocate eye movement therapy as a treatment option for dyslexia. The reliability of the clinical eye movement tests and the efficacy of the eye movement therapies have not been determined.
Saccades are the fast eye movements that move our eyes from one word to the next when we read. The eye movement recordings from patients diagnosed with reading disorders, extra ocular muscle imbalances and control patients (no learning disability or eye movement disorder) will be analyzed and compared. The sensitivity and specificity of detecting reading disorders will be determined for the Visagraph III and the Readalyzer. Although these clinical tests are frequently used to diagnose saccadic inaccuracies and diagnose dyslexia in school aged children, the validity of these clinical screening tests has not been determined.
|Condition or disease|
|Reading Disability Dyslexia|
|Study Type :||Observational|
|Actual Enrollment :||1 participants|
|Official Title:||Reliability of Clinical Eye Movement Tests as Screening Devices for Reading Disabilities|
|Study Start Date :||December 2013|
|Actual Primary Completion Date :||September 2014|
|Actual Study Completion Date :||September 2014|
Children with reading disabilities
Children diagnosed with reading disabilities (age 7 to 13).
Children with eye movement disorders
Children diagnosed with eye movement disorders (age 7 to 13).
Children with normal reading ability and normal eye movements (age 7 to 13.
- Sensitivity and specificity of clinical eye movement devices [ Time Frame: June 2014 ]The primary analysis will be determining the sensitivity and specificity of the eye movement recording devices to recognize reading disorders. The sensitivity (true positive rate) of the eye movement recorders will be determined by the ability of each device to recognize children with reading disorders in Group 1. The specificity of the recorders will be determined by calculating the false positives in group 2 (eye movement disorders), and group 3 (control subjects).
- Comparison of eye movement characteristics amongst patients with reading disorders, eye movement abnormalities and control subjects. [ Time Frame: June 2014 ]
The secondary analysis will be a study group comparison of eye movement results for each reading variable using an analysis of covariance (ANCOVA) model. The 6 calculated reading variables are listed below and will be individually compared amongst the three groups.
i. Fixations / 100 words ii. Regressions / 100 words iii. Average span of recognition iv. Average duration of fixation v. Reading rate with comprehension vi. Grade level Efficiency
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01860027
|United States, California|
|San Diego, California, United States, 92130|
|Principal Investigator:||Gregory Ostrow, MD||Scripps Clinic|
|Study Director:||Laura Kirkeby, Orthoptics||Scripps Clinic|