Early Detection of Cognitive Dysfunction in Diabetes
The rate of cognitive decline due to ageing is increased 1.5-fold to 2.0-fold in individuals with type 2 diabetes.There are no established specific treatment measures to prevent or ameliorate cognitive impairments in patients with diabetes. we want to detecte early clinical dementia in diabete.
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||Study of Cognitive Dysfunction and Diabetes|
- MMSE Olfactory function dementia [ Time Frame: 2 years ] [ Designated as safety issue: Yes ]MMSE,Olfactory function and PET(fMRI) were observed.
Biospecimen Retention: None Retained
|Study Start Date:||January 2012|
|Estimated Study Completion Date:||December 2014|
|Estimated Primary Completion Date:||December 2014 (Final data collection date for primary outcome measure)|
control,MCI, Olfactory dsfunction
There are different groups:control,MCI, Olfactory dsfunction.
control and MCI group.Glycaemic control
control and MCI
treatment and without treatment
MCI and Olfactory function
observation between MCI and Olfactory function groups.
Clinically relevant cognitive decrements in relation to diabetes mainly occur during two crucial periods in life: the period of brain development in childhood, and the period when the brain undergoes neurodegenerative changes associated with ageing.Potential leads for treatment are to optimise glycaemic control and avoid and treat vascular risk factors.we want to detecte early clinical dementia in diabete by MMSE and Olfactory function.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01830998
|Contact: xuzhipeng Wuqiang lihonghua, firstname.lastname@example.org|
|tongji Medical University||Enrolling by invitation|
|Wuhan, Hubei, China, 430074|
|Wuhan general hospital of Guangzhou Command||Recruiting|
|Wuhan, Hubei, China, 430070|
|Contact: xu zhi peng, doctor 13871168392 email@example.com|
|Wuhan general hospital of Guangzhou command||Active, not recruiting|
|Wuhan,chongqing, Hubei, China, 430070|