We updated the design of this site on September 25th. Learn more.
Show more
ClinicalTrials.gov
ClinicalTrials.gov Menu

Early Detection of Cognitive Dysfunction in Diabetes

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified December 2014 by zhipeng xu, Wuhan General Hospital of Guangzhou Military Command.
Recruitment status was:  Recruiting
Sponsor:
ClinicalTrials.gov Identifier:
NCT01830998
First Posted: April 12, 2013
Last Update Posted: December 10, 2014
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
zhipeng xu, Wuhan General Hospital of Guangzhou Military Command
  Purpose
The rate of cognitive decline due to ageing is increased 1.5-fold to 2.0-fold in individuals with type 2 diabetes.There are no established specific treatment measures to prevent or ameliorate cognitive impairments in patients with diabetes. we want to detecte early clinical dementia in diabete.

Condition
Dementia DM MCI

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Study of Cognitive Dysfunction and Diabetes

Resource links provided by NLM:


Further study details as provided by zhipeng xu, Wuhan General Hospital of Guangzhou Military Command:

Primary Outcome Measures:
  • MMSE Olfactory function dementia [ Time Frame: 2 years ]
    MMSE,Olfactory function and PET(fMRI) were observed.


Biospecimen Retention:   None Retained
serum

Estimated Enrollment: 400
Study Start Date: January 2012
Estimated Study Completion Date: December 2014
Estimated Primary Completion Date: December 2014 (Final data collection date for primary outcome measure)
Groups/Cohorts
control,MCI, Olfactory dsfunction
There are different groups:control,MCI, Olfactory dsfunction.
control, MCI
control and MCI group.Glycaemic control
control and MCI
treatment and without treatment
MCI and Olfactory function
observation between MCI and Olfactory function groups.

Detailed Description:
Clinically relevant cognitive decrements in relation to diabetes mainly occur during two crucial periods in life: the period of brain development in childhood, and the period when the brain undergoes neurodegenerative changes associated with ageing.Potential leads for treatment are to optimise glycaemic control and avoid and treat vascular risk factors.we want to detecte early clinical dementia in diabete by MMSE and Olfactory function.
  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   50 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
Patients with type 2 diabetes
Criteria

Inclusion Criteria:

  • Patients with type 2 diabetes(Age>50 years)

Exclusion Criteria:

  • with stroke or other complications.
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01830998


Contacts
Contact: xuzhipeng Wuqiang lihonghua, doctor 13871168392 21823074@qq.com

Locations
China, Hubei
Wuhan general hospital of Guangzhou command Active, not recruiting
Wuhan,chongqing, Hubei, China, 430070
Wuhan general hospital of Guangzhou Command Recruiting
Wuhan, Hubei, China, 430070
Contact: xu zhi peng, doctor    13871168392    xzhp14@sohu.com   
tongji Medical University Enrolling by invitation
Wuhan, Hubei, China, 430074
Sponsors and Collaborators
Wuhan General Hospital of Guangzhou Military Command
  More Information

Responsible Party: zhipeng xu, doctor, Wuhan General Hospital of Guangzhou Military Command
ClinicalTrials.gov Identifier: NCT01830998     History of Changes
Other Study ID Numbers: 20130401
First Submitted: April 1, 2013
First Posted: April 12, 2013
Last Update Posted: December 10, 2014
Last Verified: December 2014

Keywords provided by zhipeng xu, Wuhan General Hospital of Guangzhou Military Command:
Dementia
Olfactory

Additional relevant MeSH terms:
Dementia
Cognitive Dysfunction
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Neurocognitive Disorders
Mental Disorders
Cognition Disorders